Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | NPY4R | P50391 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29428932 | 0.84 | ALDH1A1 (0.54) | ALDH1A1THRBLMNANPY1RNPY2R | |
| SCHEMBL20995905 | 0.80 | ALDH1A1 (0.50) | ALDH1A1THRBLTA4HLMNANPY1R | |
| SCHEMBL14305104 | 0.79 | HRH1 (0.47) | HRH1SLC6A2SLC6A3 | |
| SCHEMBL21357944 | 0.76 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL3948636 | 0.73 | MAPT (0.46) | ALDH1A1THRBMAPK1 | |
| SCHEMBL10781873 | 0.73 | ALDH1A1 (0.49) | ALDH1A1THRBLMNANPY1RNPY2R | |
| SCHEMBL28570110 | 0.72 | NPY1R (0.62) | ALDH1A1THRBLMNANPY1RNPY2R | |
| SCHEMBL1496724 | 0.72 | NPY1R (0.62) | ALDH1A1THRBLMNANPY1RNPY2R | |
| SCHEMBL19381817 | 0.72 | ALDH1A1 (0.44) | ALDH1A1THRBLTA4HLMNANPY1R | |
| SCHEMBL20995934 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065196-A1 | AMIDE COMPOUNDS | DGAT2, DGAT1, DLAT | ALDH1A1 272/4885THRB 2355/4885HCRTR2 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.