Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethane SCHEMBL8174121 | 0.77 | GPR3 (0.46) | GPR3HTR2APOLB | |
| Hydrochloric Acid SCHEMBL27502080 | 0.76 | GPR3 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL6554040 | 0.76 | GPR3 (0.35) | GPR3HTR2APOLB | |
| Hydrochloric Acid SCHEMBL6553648 | 0.76 | GPR3 (0.35) | GPR3HTR2APOLB | |
| Hydrochloric Acid SCHEMBL540484 | 0.76 | GPR3 (0.44) | GPR3HTR2APOLB | |
| SCHEMBL27602853 | 0.76 | GPR3 (0.37) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL4062875 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL4633012 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Hydrochloric Acid SCHEMBL4093570 | 0.74 | GPR3 (0.35) | GPR3HTR2APOLBPBRM1TNKS2 | |
| Toluene SCHEMBL27459088 | 0.74 | LMNA (0.48) | GPR3HTR2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1013581-B | SOLID CATALYST FOR POLYMERIZING OLEFIN | MITSUI PETROCHEMICAL IND (JP) | 1991-08-21 | — | — | CN | claimed |
| CN-116970107-A | Catalyst combination and method for preparing poly alpha-olefin synthetic oil by using same | 万华化学集团股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2009104782-A1 | ETHYLENE HOMOPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104785-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| WO-2009104783-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-08-27 | — | — | WO | disclosed |
| CN-1882619-A | New (co)polymer, method for producing the same, and method for producing carboxyl group-containing (co)polymer | JSR CORP (JP) | 2006-12-20 | — | — | CN | disclosed |
| CN-1152897-C | Propylene/ethylene-a-olefin block copolymer and process for producing the same | ס�ѻ�ѧ��ҵ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |
| CN-1274360-A | Processes for prepn. of metallocene complexes | CHISSO CORP (JP) | 2000-11-22 | — | — | CN | disclosed |
| CN-1049899-C | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 2000-03-01 | — | — | CN | disclosed |
| CN-1170008-A | Propylene/ethylene-a-olefin block copolymer and process for producing the same | SUMITOMO CHEMICAL CO (JP) | 1998-01-14 | — | — | CN | disclosed |
| CN-1128272-A | Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins | DSM NV (NL) | 1996-08-07 | — | — | CN | disclosed |
| CN-1031278-C | Modified polyolefin particles and process for preparation thereof | MITSUI PETROCHEMICAL IND (JP) | 1996-03-13 | — | — | CN | disclosed |
| CN-1016347-B | Olefin polymerization catalyst and polymerization method thereof | MITSUI PETROCHEMICAL IND (JP) | 1992-04-22 | — | — | CN | disclosed |
| CN-1013581-B | SOLID CATALYST FOR POLYMERIZING OLEFIN | MITSUI PETROCHEMICAL IND (JP) | 1991-08-21 | — | — | CN | disclosed |
| CN-1013580-B | PROCESS FOR POLYMERIZATING OLEFINE | MITSUI PETROCHEMICAL IND (JP) | 1991-08-21 | — | — | CN | disclosed |
| CN-1043144-A | Modified polyolefin particles and preparation method thereof | MITSUI PETROCHEMICAL IND (JP) | 1990-06-20 | — | — | CN | disclosed |
| CN-1036016-A | The polymerization process of alkene | MITSUI PETROCHEMICAL IND (JP) | 1989-10-04 | — | — | CN | disclosed |
| CN-1035297-A | Olefin polymerization catalysis and polymerization process thereof | MITSUI PETROCHEMICAL IND (JP) | 1989-09-06 | — | — | CN | disclosed |
| CN-88103902-A | The solid catalyst of olefinic polymerization | — | 1988-12-14 | — | — | CN | disclosed |
| EP-0287666-A1 | PROCESS FOR POLYMERIZING OLEFINS | Mitsui Chemicals, Inc. (JP) | 1988-10-26 | — | — | EP | disclosed |