Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4072414 | 0.77 | MPO (0.47) | HDAC1MPOCYP3A4KDM5ABLM | |
| SCHEMBL217496 | 0.76 | NNMT (0.49) | HCAR3HCAR2HDAC1NNMTMPO | |
| SCHEMBL31141613 | 0.74 | HDAC1 (0.57) | HCAR3HDAC1GFERALDH1A1 | |
| SCHEMBL4070958 | 0.73 | HCAR3 (0.63) | HCAR3MPOCYP3A4KDM5ABLM | |
| SCHEMBL4081019 | 0.73 | PRSS1 (0.49) | HDAC1MPOCYP3A4KDM5ABLM | |
| SCHEMBL15059555 | 0.72 | HCAR3 (0.61) | HCAR3HCAR2NNMT | |
| SCHEMBL18511954 | 0.72 | HDAC1 (0.55) | HDAC1ALDH1A1 | |
| SCHEMBL25212859 | 0.72 | HCAR3 (0.53) | HCAR3NNMTMPOCYP3A4KDM5A | |
| SCHEMBL31292064 | 0.72 | HCAR3 (0.73) | HCAR3HCAR2 | |
| SCHEMBL4079962 | 0.72 | PRSS1 (0.50) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009155362-A1 | SMALL MOLECULE HEMATOPOIETIC GROWTH FACTOR MIMETIC COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2009-12-23 | — | — | WO | disclosed |