Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4075285 | 0.86 | DRD3 (0.57) | DRD2ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL4254856 | 0.82 | DRD2 (0.56) | DRD2ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL4079163 | 0.80 | DRD2 (0.60) | DRD2HTR2ADRD3HTR1AHTR7 | |
| SCHEMBL4079160 | 0.80 | DRD2 (0.60) | DRD2HTR2ADRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4079619 | 0.79 | DRD2 (0.59) | DRD2HTR2ADRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4079616 | 0.79 | DRD2 (0.59) | DRD2HTR2ADRD3HTR1AHTR7 | |
| SCHEMBL4084481 | 0.79 | DRD2 (0.58) | DRD2ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL4075532 | 0.78 | DRD2 (0.54) | DRD2ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL4079602 | 0.75 | HTR7 (0.55) | DRD2HTR2ADRD3HTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4076870 | 0.74 | HTR1A (0.54) | DRD2HTR2ADRD3HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |
| EP-1438302-B1 | NEW SULFONAMIDE DERIVATIVES AS D3-RECEPTOR LIGANDS | RICHTER GEDEON NYRT (HU) | 2012-05-30 | — | — | EP | disclosed |