Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418684 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL3314375 | 0.70 | — | — | |
| SCHEMBL27923946 | 0.69 | TSHR (0.38) | — | |
| SCHEMBL1104735 | 0.69 | — | — | |
| SCHEMBL11431867 | 0.69 | TSHR (0.44) | — | |
| SCHEMBL9034708 | 0.69 | ALDH1A1 (0.45) | — | |
| SCHEMBL3318616 | 0.69 | ALDH1A1 (0.53) | — | |
| SCHEMBL996015 | 0.69 | — | — | |
| SCHEMBL27093902 | 0.67 | TSHR (0.50) | EPHX1 | |
| SCHEMBL7517899 | 0.67 | SMN1; SMN2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117831-A9 | HYBRID MOLECULES HAVING MIXED VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITORY PROPERTIES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2009-12-30 | — | — | WO | disclosed |
| WO-2009117831-A1 | HYBRID MOLECULES HAVING MIXED VITAMIN D RECEPTOR AGONISM AND HISTONE DEACETYLASE INHIBITORY PROPERTIES | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2009-10-01 | — | — | WO | disclosed |