Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414965 | 0.86 | ACHE (0.55) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL24689747 | 0.84 | ACHE (0.52) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL2922149 | 0.82 | RAB9A (0.52) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL5025375 | 0.80 | HTR7 (0.55) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL9876129 | 0.78 | CNR2 (0.51) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL7188023 | 0.77 | NPC1 (0.46) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL5708395 | 0.77 | CNR2 (0.47) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL18574523 | 0.77 | RAB9A (0.46) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL20786829 | 0.77 | CNR2 (0.46) | ACHERAB9ANPC1SMN1; SMN2HPGD | |
| SCHEMBL11789785 | 0.77 | RAB9A (0.46) | ACHERAB9ANPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650565-B2 | Carbazole compound and use thereof | TOSOH CORPORATION (JP) | 2017-05-16 | — | — | US | disclosed |
| US-8993805-B2 | Benzofluorene compound and use thereof | TOSOH CORPORATION (JP) | 2015-03-31 | — | — | US | disclosed |
| EP-2492260-A1 | CARBAZOLE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20120203010-A1 | CARBAZOLE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2012-08-09 | — | — | US | disclosed |
| EP-2006278-A9 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-2006278-A2 | BENZOFLUORENE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2008-12-24 | — | — | EP | disclosed |
| US-7189877-B2 | Arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSCH CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| EP-1400578-B1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | TOSOH CORP (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | ACHE 3669/4885RAB9A 1907/4885NPC1 2320/4885 |
| US-20090184312-A1 | BENZOFLUORENE COMPOUND AND USE THEREOF | SLC7A1, SLC43A1, SLC7A5 | ACHE 4701/4885RAB9A 1656/4885NPC1 439/4885 |
| US-20120203010-A1 | CARBAZOLE COMPOUND AND USE THEREOF | AR, DRD3, AHR | ACHE 2609/4885RAB9A 2533/4885NPC1 1844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.