SCHEMBL7188023

SCHEMBL7188023

Cc1cccc(-c2ccccc2[O])c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
CNR2 P34972 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
ACHE P22303 1/20 0.44
MAOB P27338 1/20 0.44
ENPP3 O14638 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
CNR1 P21554 2/20 0.42
FYN P06241 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42
DYRK1B Q9Y463 2/20 0.42
CHEK1 O14757 1/20 0.42
MAP4K4 O95819 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28414965 0.84 ACHE (0.55) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL8617214 0.83 BRD9 (0.46) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL24689747 0.82 ACHE (0.52) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL2922149 0.80 RAB9A (0.52) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL11898487 0.79 ALDH1A1 (0.42) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL5025375 0.78 HTR7 (0.55) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL9936642 0.78 PTGER1 (0.49) NPC1RAB9ASMN1; SMN2ALDH1A1MAPT
SCHEMBL9876129 0.77 CNR2 (0.51) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL4080997 0.77 ACHE (0.46) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1
SCHEMBL10417158 0.76 TRPA1 (0.46) NPC1RAB9ACNR2SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100460422-C Catalytic components for polymerization of olefins, catalyst and process for the polymerization MARUZEN PETROCHEM CO LTD (JP) 2009-02-11 CN disclosed
US-6627714-B2 Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer MARUZEN PETROCHEMICAL CO., LTD. (JP) 2003-09-30 US disclosed
US-20020058767-A1 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-16 US disclosed
EP-1205497-A2 Method for producing an olefin type copolymer having a cyclic structure MARUZEN PETROCHEMICAL CO., LTD. (JP) 2002-05-15 EP disclosed
CN-1282340-A Solid catalysts for polymerization of olefins and process for production of olefin polymers therewith MARUZEN PETROCHEM CO LTD (JP) 2001-01-31 CN disclosed
EP-1051394-A1 POTASSIUM CHANNEL INHIBITORS Icagen, Inc. (US) 2000-11-15 EP disclosed
WO-1999037607-A1 POTASSIUM CHANNEL INHIBITORS ICAGEN, INC. (US) 1999-07-29 WO disclosed