Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FSHR | P23945 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074159 | 0.91 | SSTR4 (0.39) | EPHX2MEN1KMT2ATSHRHDAC1 | |
| SCHEMBL4074093 | 0.91 | MEN1 (0.38) | HPGDEPHX2ENPP2MEN1KMT2A | |
| SCHEMBL205569 | 0.89 | ENPP2 (0.46) | THRBHPGDEPHX2ENPP2MEN1 | |
| SCHEMBL5157752 | 0.84 | EPHX2 (0.44) | THRBHPGDEPHX2MEN1KMT2A | |
| Butane SCHEMBL4081062 | 0.82 | SIGMAR1 (0.39) | THRBHPGDEPHX2MEN1KMT2A | |
| SCHEMBL206628 | 0.80 | SSTR4 (0.42) | HPGDENPP2MEN1KMT2ATSHR | |
| SCHEMBL206649 | 0.80 | ENPP2 (0.44) | HPGDENPP2MEN1KMT2ASIGMAR1 | |
| SCHEMBL206966 | 0.79 | EPHX2 (0.62) | THRBHPGDEPHX2MEN1KMT2A | |
| SCHEMBL207303 | 0.77 | SIGMAR1 (0.46) | THRBHPGDEPHX2MEN1KMT2A | |
| SCHEMBL206620 | 0.77 | EPHX2 (0.46) | THRBHPGDEPHX2SIGMAR1SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | claimed |
| EP-1745010-B1 | SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-08-05 | — | — | EP | disclosed |