Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.85 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.76 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4088459 | 1.00 | TRPM8 (0.85) | TRPM8TRPV1KCNA5 | |
| SCHEMBL4083810 | 1.00 | TRPM8 (0.85) | TRPM8TRPV1KCNA5 | |
| SCHEMBL18552997 | 0.92 | TRPM8 (1.00) | TRPM8TRPV1 | |
| SCHEMBL22289417 | 0.92 | TRPM8 (1.00) | TRPM8TRPV1 | |
| SCHEMBL469344 | 0.92 | TRPM8 (1.00) | TRPM8TRPV1 | |
| SCHEMBL15103207 | 0.92 | TRPM8 (1.00) | TRPM8TRPV1 | |
| SCHEMBL4088451 | 0.85 | TRPV1 (0.74) | TRPM8TRPV1 | |
| SCHEMBL11886340 | 0.85 | TRPV1 (0.74) | TRPM8TRPV1 | |
| SCHEMBL11886519 | 0.85 | TRPV1 (0.74) | TRPM8TRPV1 | |
| SCHEMBL11886341 | 0.85 | TRPV1 (0.74) | TRPM8TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | claimed |
| EP-2064959-B1 | Aromatic Neomenthylamides as flavouring agents | SYMRISE AG (DE) | 2012-07-25 | — | — | EP | claimed |
| EP-2064959-A1 | Aromatic Neomenthylamides as flavouring agents | Symrise GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | claimed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | claimed |
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| US-8871288-B2 | Aromatic neomenthylamides as flavoring substances | SYMRISE AG (DE) | 2014-10-28 | — | — | US | disclosed |
| EP-2064959-B1 | Aromatic Neomenthylamides as flavouring agents | SYMRISE AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2064959-A1 | Aromatic Neomenthylamides as flavouring agents | Symrise GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2064959-A1 | Aromatic Neomenthylamides as flavouring agents | Symrise GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| CN-101422229-A | Romatic neomenthylamides as flavouring agents | SYMRISE GMBH & CO KG (DE) | 2009-05-06 | — | — | CN | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | SYMRISE GMBH & CO. KG (DE) | 2009-04-30 | — | — | US | disclosed |
| US-20080319055-A1 | Cooling Compounds | GIVAUDAN SA (CH) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090110796-A1 | AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES | AOC3, NPR3, AOC2 | TRPM8 1514/4885TRPV1 716/4885KCNA5 2023/4885 |
| US-20080319055-A1 | Cooling Compounds | TAS2R1, TAS2R43, TAS2R3 | TRPM8 131/4885TRPV1 40/4885KCNA5 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.