SCHEMBL4088451

SCHEMBL4088451

COC(=O)c1ccc(C(=O)NC2CC(C)CCC2C(C)C)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 11/20 0.74
TRPM8 Q7Z2W7 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11886519 1.00 TRPV1 (0.74) TRPV1TRPM8
SCHEMBL11886341 1.00 TRPV1 (0.74) TRPV1TRPM8
SCHEMBL11886340 1.00 TRPV1 (0.74) TRPV1TRPM8
SCHEMBL4311591 0.88 TRPV1 (0.76) TRPV1TRPM8
SCHEMBL4088459 0.85 TRPM8 (0.85) TRPV1TRPM8
SCHEMBL4081078 0.85 TRPM8 (0.85) TRPV1TRPM8
SCHEMBL4083810 0.85 TRPM8 (0.85) TRPV1TRPM8
SCHEMBL4078851 0.84 TRPV1 (0.67) TRPV1TRPM8
SCHEMBL4083683 0.84 TRPV1 (0.67) TRPV1TRPM8
SCHEMBL15103207 0.83 TRPM8 (1.00) TRPV1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US disclosed
EP-4593631-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME Mars, Incorporated (US) 2025-08-06 EP disclosed
CN-119968127-A Animal food compositions with improved palatability and customizable properties and methods of making the same 玛氏公司 2025-05-09 CN disclosed
WO-2024073025-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-04 WO disclosed
EP-4344552-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2024-04-03 EP disclosed
US-8871288-B2 Aromatic neomenthylamides as flavoring substances SYMRISE AG (DE) 2014-10-28 US disclosed
US-8871288-B2 Aromatic neomenthylamides as flavoring substances SYMRISE AG (DE) 2014-10-28 US disclosed
US-8871288-B2 Aromatic neomenthylamides as flavoring substances SYMRISE AG (DE) 2014-10-28 US disclosed
EP-2064959-B1 Aromatic Neomenthylamides as flavouring agents SYMRISE AG (DE) 2012-07-25 EP disclosed
EP-2064959-B1 Aromatic Neomenthylamides as flavouring agents SYMRISE AG (DE) 2012-07-25 EP disclosed
EP-2064959-A1 Aromatic Neomenthylamides as flavouring agents Symrise GmbH & Co. KG (DE) 2009-06-03 EP disclosed
US-20090110796-A1 AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2009-04-30 US disclosed
US-20090110796-A1 AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2009-04-30 US disclosed
US-20090110796-A1 AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2009-04-30 US disclosed
US-20080319055-A1 Cooling Compounds GIVAUDAN SA (CH) 2008-12-25 US disclosed
US-20080319055-A1 Cooling Compounds GIVAUDAN SA (CH) 2008-12-25 US disclosed
US-20080319055-A1 Cooling Compounds GIVAUDAN SA (CH) 2008-12-25 US disclosed
US-20080292763-A1 Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance SYMRISE GMBH & CO. KG (DE) 2008-11-27 US disclosed
US-20080292763-A1 Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance SYMRISE GMBH & CO. KG (DE) 2008-11-27 US disclosed
EP-1989944-A1 Substituted cyclopropane carbolic acid(3-methyl-cyclohexyl)amides as taste substances Symrise GmbH & Co. KG (DE) 2008-11-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090110796-A1 AROMATIC NEOMENTHYLAMIDES AS FLAVORING SUBSTANCES AOC3, NPR3, AOC2 TRPV1 716/4885TRPM8 1514/4885
US-20080319055-A1 Cooling Compounds TAS2R1, TAS2R43, TAS2R3 TRPV1 40/4885TRPM8 131/4885
US-20080292763-A1 Substituted Cyclopropanecarboxylic acid (3-methyl-cyclohexyl)amide as flavoring substance TAS1R1, TAS2R1, TAS1R3 TRPV1 279/4885TRPM8 477/4885
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME PIGS, TAS2R13, CEL TRPV1 3291/4885TRPM8 3857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.