Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2205657 | 0.85 | HIF1A (0.37) | HIF1ACYSLTR2CYSLTR1HTR1DHTR1B | |
| SCHEMBL19693446 | 0.76 | TP53 (0.43) | TSHRLMNASMN1; SMN2 | |
| SCHEMBL10113414 | 0.76 | KMT2A (0.66) | KMT2A | |
| SCHEMBL3970375 | 0.76 | FFAR4 (0.45) | ALDH1A1KDM4E | |
| SCHEMBL3972838 | 0.75 | SLC2A1 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL4568773 | 0.73 | KMT2A (0.49) | HIF1ACYSLTR2CYSLTR1KMT2AALDH1A1 | |
| SCHEMBL18539785 | 0.73 | HIF1A (0.47) | HIF1AKMT2ATSHRKDM4EMTNR1A | |
| SCHEMBL17138148 | 0.73 | HIF1A (0.47) | HIF1ATSHRKDM4EMTNR1AMTNR1B | |
| SCHEMBL28465737 | 0.72 | CHRNB2 (0.49) | HIF1A | |
| SCHEMBL4081168 | 0.72 | MTNR1A (0.53) | HTR1DHTR1BALDH1A1KDM4EMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009045479-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. (US) | 2009-04-09 | — | — | WO | disclosed |