Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4085111 | 0.80 | IMPDH2 (0.35) | IMPDH2XDHABCC1TSHRNPSR1 | |
| SCHEMBL4084945 | 0.80 | DYRK1A (0.41) | IMPDH2XDHALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8266974 | 0.72 | IMPDH2 (0.61) | IMPDH2XDHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31106988 | 0.72 | IMPDH2 (0.61) | IMPDH2XDHALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13885170 | 0.70 | JAK2 (0.35) | XDHABCC1 | |
| SCHEMBL21076079 | 0.68 | CA1 (0.39) | IMPDH2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL25784287 | 0.66 | BCHE (0.40) | ALDH1A1MAPTTDP1TSHR | |
| SCHEMBL21725642 | 0.65 | HTR2A (0.36) | ALDH1A1SMN1; SMN2KDM4ETDP1CA1 | |
| SCHEMBL14547575 | 0.63 | TSHR (0.48) | ALDH1A1MAPTSMN1; SMN2KDM4ECA1 | |
| SCHEMBL1626174 | 0.63 | ALDH1A1 (0.36) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |