Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082959 | 0.80 | IMPDH2 (0.38) | IMPDH2XDHKDM4EALDH1A1TDP1 | |
| SCHEMBL20605101 | 0.79 | IMPDH2 (0.54) | DYRK1AIMPDH2KDM4EALDH1A1TDP1 | |
| SCHEMBL4085111 | 0.76 | IMPDH2 (0.35) | IMPDH2XDHABCC1 | |
| SCHEMBL4094763 | 0.76 | PDE4B (0.32) | ALDH1A1 | |
| SCHEMBL4095238 | 0.76 | KCNH2 (0.35) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8266974 | 0.73 | IMPDH2 (0.61) | IMPDH2XDHALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL31106988 | 0.73 | IMPDH2 (0.61) | IMPDH2XDHALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL4095742 | 0.71 | BRD4 (0.40) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24853984 | 0.69 | SMN1; SMN2 (0.53) | XDHALDH1A1SMN1; SMN2 | |
| SCHEMBL30173392 | 0.69 | SMN1; SMN2 (0.53) | XDHALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |