Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK7 | P50613 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4083502 | 0.82 | SLC6A2 (0.33) | SLC6A2CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL3990522 | 0.82 | CYP2D6 (0.38) | SLC6A2TP53CYP1A2CYP2D6KMT2A | |
| SCHEMBL323754 | 0.65 | ALDH1A1 (0.41) | TP53CYP1A2CYP2D6HTTKMT2A | |
| SCHEMBL4436881 | 0.62 | CYP2D6 (0.47) | TP53CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL4078343 | 0.62 | SLC6A2 (0.33) | SLC6A2CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL19089318 | 0.61 | EGFR (0.55) | TP53CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL632053 | 0.61 | ASIC3 (0.59) | TP53CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL29392239 | 0.61 | ASIC3 (0.59) | TP53CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL2988060 | 0.60 | CLK4 (0.43) | TP53CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL4429838 | 0.59 | CYP2D6 (0.44) | TP53CDC7DAPK3MAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |