Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082995 | 0.82 | SLC6A2 (0.36) | SLC6A2CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL3990522 | 0.78 | CYP2D6 (0.38) | SLC6A2SMN1; SMN2CYP1A2CYP2C19MEN1 | |
| SCHEMBL7036048 | 0.67 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19089318 | 0.67 | EGFR (0.55) | CDC7DAPK3MAP4K4PIM1PRKACA | |
| SCHEMBL4078343 | 0.64 | SLC6A2 (0.33) | SLC6A2CDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL4014784 | 0.64 | ALDH1A1 (0.35) | SMN1; SMN2CYP1A2ALOX15CYP2C19MEN1 | |
| SCHEMBL29392239 | 0.63 | ASIC3 (0.59) | CDC7DAPK3MAP4K4PIM1PRKACA | |
| SCHEMBL632053 | 0.63 | ASIC3 (0.59) | CDC7DAPK3MAP4K4PIM1PRKACA | |
| SCHEMBL700437 | 0.61 | GPR3 (0.41) | SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL16397985 | 0.61 | KDM4E (0.56) | CDC7DAPK3MAP4K4PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |