SCHEMBL4083756

SCHEMBL4083756

C=CCc1cc(Cl)cc(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
XDH P47989 1/20 0.41
IDO1 P14902 2/20 0.41
ALDH1A1 P00352 5/20 0.40
PPARG P37231 2/20 0.40
PPARD Q03181 2/20 0.40
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
ALDH2 P05091 1/20 0.40
GAA P10253 1/20 0.40
GABRA1 P14867 1/20 0.40
AKR1B1 P15121 1/20 0.40
HPGD P15428 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
GABRB2 P47870 1/20 0.40
KMT2A Q03164 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
RAB9A P51151 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22082789 0.84 CYP3A4 (0.48) TSHRXDHIDO1ALDH1A1PPARG
SCHEMBL29242841 0.84 XDH (0.35) TSHRXDHIDO1ALDH1A1PPARG
SCHEMBL215399 0.80 XDH (0.50) TSHRXDHALDH1A1PPARGPPARD
SCHEMBL771274 0.77 PNMT (0.54) XDHIDO1ALDH1A1PPARGPPARD
SCHEMBL6824954 0.77 XDH (0.36) TSHRXDHALDH1A1PPARGPPARD
SCHEMBL2654048 0.76 TSHR (0.44) TSHRIDO1CNR1RAB9ACYP3A4
SCHEMBL22469881 0.75 XDH (0.39) TSHRXDHALDH1A1PPARGPPARD
SCHEMBL10873667 0.75 XDH (0.39) TSHRXDHALDH1A1PPARGPPARD
SCHEMBL1427989 0.74 ALDH1A1 (0.52) TSHRXDHIDO1ALDH1A1PPARG
SCHEMBL862044 0.74 XDH (0.41) TSHRXDHIDO1ALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115957616-B Desulfurizing filler and preparation and application thereof 中国石油化工股份有限公司 2025-03-04 CN claimed
CN-115957725-A Modified hollow ceramic fiber and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957616-A Desulfurization filler and preparation and application thereof 中国石油化工股份有限公司 2023-04-14 CN claimed
CN-115957616-A Desulfurization filler and preparation and application thereof 中国石油化工股份有限公司 2023-04-14 CN disclosed
CN-115957725-A Modified hollow ceramic fiber and preparation method and application thereof 中国石油化工股份有限公司 2023-04-14 CN disclosed
EP-1559701-B1 Process for producing alkylaromatic compound MITSUBISHI GAS CHEMICAL CO (JP) 2014-10-08 EP disclosed
US-7518025-B2 Process for producing alkyl aromatic compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-04-14 US disclosed
US-20060122439-A1 Process for producing alkylaromatic compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-06-08 US disclosed
EP-1559701-A1 PROCESS FOR PRODUCING ALKYLAROMATIC COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2005-08-03 EP disclosed
EP-1013636-B1 Preparation of allylic aromatic compounds AMERSHAM HEALTH AS (NO) 2003-07-09 EP disclosed
US-6284894-B1 AROMATIC AMINE IS REACTED FIRST WITH A NITRITE AND THEN WITH AN ALLYLIC OLEFIN HAVING AN ELIMINATABLE TERMINAL SUBSTITUENT. NYCOMED IMAGING AS (NO) 2001-09-04 US disclosed
EP-1013636-A1 Preparation of allylic aromatic compounds NYCOMED IMAGING AS (NO) 2000-06-28 EP disclosed
US-5030777-A Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene STANDARD CHLORINE OF DELAWARE, INC. (US) 1991-07-09 US disclosed
US-5030777-A Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene STANDARD CHLORINE OF DELAWARE, INC. (US) 1991-07-09 US disclosed
US-5030777-A Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene STANDARD CHLORINE OF DELAWARE, INC. (US) 1991-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122439-A1 Process for producing alkylaromatic compound DDC, RNF5, DDT TSHR 2462/4885XDH 2067/4885IDO1 944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.