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Ribose (Furanose)

Ribose (Furanose)

SCHEMBL4083935

Nc1cnnc(=O)[nH]1.OC[C@H]1OC(O)[C@H](O)[C@@H]1O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 3/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ PNP P00491 3/20 0.39
▸ MTOR P42345 2/20 0.38
▸ THRB P10828 1/20 0.38
▸ MDM2 Q00987 1/20 0.38
▸ NCOA1 Q15788 1/20 0.38
▸ NCOA3 Q9Y6Q9 1/20 0.38
▸ GMNN O75496 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ DNMT1 P26358 1/20 0.38
▸ THPO P40225 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ BLM P54132 1/20 0.38
▸ HBB P68871 1/20 0.38
▸ PMP22 Q01453 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4081537 0.74 — —
Ribose (Furanose) SCHEMBL4087975 0.74 CDA (0.39) LMNASMN1; SMN2ALDH1A1POLBPNP
Ribose (Furanose) SCHEMBL3673370 0.74 KDM4E (0.44) LMNASMN1; SMN2ALDH1A1POLBMTOR
Ribose (Furanose) SCHEMBL1814863 0.71 ADK (0.44) LMNASMN1; SMN2ALDH1A1POLBPNP
Ribose (Furanose) SCHEMBL16982462 0.67 LGALS1 (0.50) LMNAALDH1A1
Ribose (Furanose) SCHEMBL23017520 0.67 LGALS1 (0.54) LMNAALDH1A1
Ribose (Furanose) SCHEMBL14349491 0.67 LGALS1 (0.54) LMNAALDH1A1
Ribose (Furanose) SCHEMBL7618455 0.67 LGALS1 (0.54) LMNAALDH1A1
Ribose (Furanose) SCHEMBL109435 0.67 LGALS1 (0.54) LMNAALDH1A1
Ribose (Furanose) SCHEMBL12878699 0.67 LGALS1 (0.54) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491818-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2009-02-17 — — US disclosed
US-7423143-B2 Nucleic acid labeling compounds AFFYMETRIX. INC. (US) 2008-09-09 — — US disclosed
US-7291463-B2 Incubating/condensating pseudoisocytidine molecule with (1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride to provide a pseudouridine molecule; oncology diagnosis AFFYMETRIX, INC. (US) 2007-11-06 — — US disclosed
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 — — US disclosed
US-7179905-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-02-20 — — US disclosed
US-20050287563-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-12-29 — — US disclosed
US-6965020-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2005-11-15 — — US disclosed
EP-1589025-A2 Nucleic acid labeling compounds Affymetrix, Inc. (US) 2005-10-26 — — EP disclosed
US-20050164268-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2005-07-28 — — US disclosed
EP-1124838-B1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX INC (US) 2005-06-01 — — EP disclosed
US-20040002595-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2004-01-01 — — US disclosed
US-20030232979-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2003-12-18 — — US disclosed
US-20030180757-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2003-09-25 — — US disclosed
US-6596856-B2 For probes, comprising a heterocycle condensed with a cyclic group such as ribofuranose derivative; biotin and 5-carboxyfluorescein derivatives AFFYMETRIX, INC. 2003-07-22 — — US disclosed
US-20020165372-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2002-11-07 — — US disclosed
WO-2000006771-A9 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX INC (US) 2002-08-22 — — WO disclosed
US-20010044531-A1 Nucleic acid labeling compounds AFFYMETRIX, INC. 2001-11-22 — — US disclosed
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. 2001-08-30 — — US disclosed
EP-1124838-A2 NUCLEIC ACID LABELING COMPOUNDS Affymetrix, Inc. (US) 2001-08-22 — — EP disclosed
WO-2000006771-A2 NUCLEIC ACID LABELING COMPOUNDS AFFYMETRIX, INC. (US) 2000-02-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002595-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20030180757-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20050164268-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20010044531-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20050287563-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20010018514-A1 NUCLEIC ACID LABELING COMPOUNDS RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20020165372-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885
US-20030232979-A1 Nucleic acid labeling compounds RNGTT, DUT, FBL LMNA 547/4885SMN1; SMN2 1926/4885ALDH1A1 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.