SCHEMBL4084312

SCHEMBL4084312

CCCC(C)C(=O)Oc1ccccc1C

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.49
TSHR P16473 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.42
HTT P42858 1/20 0.42
POLB P06746 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PPARG P37231 2/20 0.39
BCHE P06276 1/20 0.39
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
PPARA Q07869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15548622 0.90 TSHR (0.50) TDP1TSHRL3MBTL1KDM4EALDH1A1
SCHEMBL4090840 0.87 TDP1 (0.48) TDP1ATML3MBTL1KDM4EALDH1A1
SCHEMBL15547805 0.84 PTGS2 (0.49) TDP1TSHRKDM4EALDH1A1MEN1
SCHEMBL4079499 0.84 TSHR (0.56) TSHRATML3MBTL1KDM4EALDH1A1
SCHEMBL15546830 0.84 TSHR (0.46) TDP1TSHRKDM4EALDH1A1POLB
SCHEMBL15548746 0.83 ALOX15 (0.49) TSHRL3MBTL1KDM4EALDH1A1POLB
SCHEMBL15548099 0.80 KDM4E (0.58) TSHRATML3MBTL1KDM4EALDH1A1
SCHEMBL15547130 0.80 CYP3A4 (0.49) TDP1TSHRL3MBTL1KDM4EALDH1A1
SCHEMBL1261877 0.79 MEN1 (0.51) TDP1ATML3MBTL1KDM4EALDH1A1
SCHEMBL15547208 0.79 KDM4E (0.54) TSHRKDM4EMEN1KMT2APPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210302847-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2021-09-30 US disclosed
US-10203617-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2019-02-12 US disclosed
US-9971258-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2018-05-15 US disclosed
US-20170285497-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2017-10-05 US disclosed
US-20090186138-A1 Method of Flavoring GIVAUDAN SA (CH) 2009-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090186138-A1 Method of Flavoring TAS2R5, TAS2R50, TAS2R10 TDP1 4513/4885TSHR 4345/4885ATM 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.