Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.35 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260662 | 0.81 | PTPN1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL3979067 | 0.79 | PTPN1 (0.34) | ALDH1A1 | |
| SCHEMBL4084541 | 0.76 | SYK (0.45) | MAPTTSHRHTTALDH1A1 | |
| SCHEMBL4081651 | 0.73 | LMNA (0.46) | TSHRHTTALDH1A1 | |
| SCHEMBL3972529 | 0.72 | MEN1 (0.45) | POLBKMT2A | |
| SCHEMBL3974146 | 0.70 | CYP3A4 (0.37) | ACHEKMT2AHTTALDH1A1 | |
| SCHEMBL28764389 | 0.70 | POLB (0.41) | POLBKMT2AALDH1A1 | |
| SCHEMBL3972272 | 0.69 | CA1 (0.38) | ACHEALDH1A1 | |
| SCHEMBL3973213 | 0.68 | HTR2A (0.42) | TSHRPOLBKMT2A | |
| SCHEMBL3974894 | 0.68 | HTR2A (0.44) | ACHETSHRPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |