Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081651 | 0.94 | LMNA (0.46) | SYKKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3973213 | 0.91 | HTR2A (0.42) | KDM4ELMNAMAPK1SMN1; SMN2TSHR | |
| SCHEMBL3974894 | 0.89 | HTR2A (0.44) | LMNAMAPK1SMN1; SMN2TSHRKDR | |
| SCHEMBL3973494 | 0.82 | IDH1 (0.39) | KDM4EALDH1A1HPGDHSD17B10MAPK1 | |
| SCHEMBL3972272 | 0.80 | CA1 (0.38) | ALDH1A1GAA | |
| SCHEMBL3973824 | 0.80 | HTR2A (0.36) | ALDH1A1SMN1; SMN2KDRGSK3B | |
| SCHEMBL3971360 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1HPGDHTTKDR | |
| SCHEMBL3979633 | 0.77 | POLB (0.43) | KDM4EALDH1A1HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL3973411 | 0.77 | CNR2 (0.45) | ALDH1A1HSD17B10MAPT | |
| SCHEMBL4084538 | 0.76 | MAPT (0.40) | ALDH1A1MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |