Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397863 | 0.81 | CD81 (0.33) | CD81PTGS1AKR1C3 | |
| SCHEMBL669292 | 0.81 | CD81 (0.33) | CD81PTGS1AKR1C3 | |
| SCHEMBL444192 | 0.81 | CD81 (0.33) | CD81PTGS1AKR1C3 | |
| SCHEMBL28998225 | 0.81 | LMNA (0.33) | CD81LMNAALOX15BLMPMP22 | |
| SCHEMBL304952 | 0.81 | CD81 (0.33) | CD81PTGS1AKR1C3 | |
| SCHEMBL15017599 | 0.79 | ALOX15 (0.37) | CD81ALOX15PTGS1AKR1C3 | |
| SCHEMBL212197 | 0.79 | ALOX15 (0.37) | CD81ALOX15PTGS1AKR1C3 | |
| Methacrylic Acid SCHEMBL30704265 | 0.77 | ALOX15 (0.36) | TDP1CD81ALOX15PTGS1AKR1C3 | |
| SCHEMBL27672484 | 0.77 | CD81 (0.31) | CD81LMNAALOX15BLMPMP22 | |
| SCHEMBL2119042 | 0.77 | CD81 (0.34) | CD81PTGS1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8247500-B2 | Guanidine-substituted resin for transesterification | ROHM AND HAAS COMPANY (US) | 2012-08-21 | — | — | US | disclosed |
| US-20090221844-A1 | Guanidine-substituted resin for transesterification | ROHM AND HAAS COMPANY | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221844-A1 | Guanidine-substituted resin for transesterification | CES2, ALKBH2, RNGTT | TDP1 1206/4885CD81 1410/4885LMNA 1120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.