Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095524 | 0.93 | HDAC6 (0.33) | HDAC6ABCB1HSP90AA1USP2CFTR | |
| SCHEMBL4090676 | 0.90 | HDAC6 (0.33) | HDAC6HSP90AA1 | |
| SCHEMBL12763965 | 0.89 | MEN1 (0.34) | HDAC6ABCB1HSP90AA1USP2MEN1 | |
| SCHEMBL4080660 | 0.89 | PSMB8 (0.34) | HSP90AA1USP2MEN1MAPTHPGD | |
| SCHEMBL12763962 | 0.86 | MEN1 (0.35) | ABCB1HSP90AA1USP2CFTRPAX8 | |
| SCHEMBL1095312 | 0.85 | HDAC6 (0.32) | HDAC6 | |
| SCHEMBL1095518 | 0.83 | PSMB8 (0.32) | HDAC6 | |
| SCHEMBL14078004 | 0.82 | KDM4E (0.31) | HDAC6USP2MEN1MAPTHPGD | |
| SCHEMBL12763958 | 0.82 | ACHE (0.31) | BCHEACHE | |
| SCHEMBL18258300 | 0.82 | KDM4E (0.34) | HDAC6USP2MEN1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765950-B2 | Reagents for biomolecular labeling, detection and quantification employing raman spectroscopy | PURDUE RESEARCH FOUNDATION (US) | 2014-07-01 | — | — | US | disclosed |
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | PURDUE RESEARCH FOUNDATION | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120107830-A1 | REAGENTS FOR BIOMOLECULAR LABELING, DETECTION AND QUANTIFICATION EMPLOYING RAMAN SPECTROSCOPY | SRMS, UQCRB, UQCRC1 | HDAC6 3373/4885ABCB1 315/4885HSP90AA1 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.