SCHEMBL523287

SCHEMBL523287

CCC(c1ccccc1)[Si](C)(C)Cl

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MIF P14174 1/20 0.37
TSHR P16473 1/20 0.37
AOC3 Q16853 2/20 0.36
HKDC1 Q2TB90 1/20 0.36
TRPA1 O75762 1/20 0.36
S1PR1 P21453 1/20 0.36
TAAR1 Q96RJ0 4/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
CYP19A1 P11511 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3794550 0.84 LMNA (0.46) LMNAPOLBMEN1KMT2AMIF
SCHEMBL10150940 0.81 HRH1 (0.40) LMNATSHRAOC3TRPA1TAAR1
SCHEMBL4494436 0.78 LMNA (0.45) LMNAPOLBMEN1KMT2AMIF
SCHEMBL9745875 0.76 LMNA (0.52) LMNAPOLBMEN1KMT2AMIF
SCHEMBL22283489 0.76 LMNA (0.46) LMNAPOLBMEN1KMT2AMIF
SCHEMBL15023661 0.75 AOC3 (0.41) LMNAPOLBTSHRAOC3TAAR1
SCHEMBL12999580 0.75 LMNA (0.42) LMNAPOLBMEN1KMT2AMIF
SCHEMBL9716576 0.75 LMNA (0.42) LMNAPOLBMEN1KMT2AMIF
SCHEMBL661362 0.74 LMNA (0.41) LMNAPOLBMEN1KMT2AMIF
SCHEMBL9716567 0.74 LMNA (0.41) LMNAPOLBMEN1KMT2AMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116829565-A Method for synthesizing organosilicon compounds from halosilanes 迈图高新材料公司 2023-09-29 CN disclosed
EP-2405982-B1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING (US) 2013-12-18 EP disclosed
US-8293939-B2 Methods for removing vicinal diols from lactic acid fermentation broth DOW CORNING CORPORATION (US) 2012-10-23 US disclosed
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2012-02-02 US disclosed
EP-2405982-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH Dow Corning Corporation (US) 2012-01-18 EP disclosed
WO-2010104677-A2 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH DOW CORNING CORPORATION (US) 2010-09-16 WO disclosed
US-20090030222-A1 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES WITH SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION 2009-01-29 US disclosed
EP-1979422-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS Dow Corning Corporation (US) 2008-10-15 EP disclosed
WO-2007084245-A2 SYSTEMS AND METHODS FOR FUNCTIONALIZING PARTICULATES SILANE-CONTAINING MATERIALS DOW CORNING CORPORATION (US) 2007-07-26 WO disclosed
WO-2005034205-A2 SELF ASSEMBLING NANOPARTICLE-POLYMER HYBRIDS DOW CORNING CORPORATION (US) 2005-04-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029231-A1 METHODS FOR REMOVING VICINAL DIOLS FROM LACTIC ACID FERMENTATION BROTH SORD, LDHA, LDHB LMNA 1216/4885POLB 2664/4885MEN1 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.