Citric Acid

Citric Acid

SCHEMBL4086235

Cl.O=C([O-])CC(O)(CC(=O)[O-])C(=O)[O-].[K+].[K+].[K+].[K+].[OH-]

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BHRH2IMPA1

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.80
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL5982475 0.97 CA4 (0.84) CA4ALDH1A1
Citric Acid SCHEMBL8436787 0.97 CA4 (0.84) CA4ALDH1A1
Citric Acid SCHEMBL9364269 0.97 CA4 (0.84) CA4ALDH1A1
Citric Acid SCHEMBL27913053 0.95 CA4 (0.80) CA4ALDH1A1
Citric Acid SCHEMBL27616111 0.95 CA4 (0.90) CA4ALDH1A1
Citric Acid SCHEMBL8761101 0.95 CA4 (0.90) CA4ALDH1A1
Citric Acid SCHEMBL27448234 0.95 CA4 (0.90) CA4ALDH1A1
Citric Acid SCHEMBL7004500 0.95 CA4 (0.89) CA4ALDH1A1
Citric Acid SCHEMBL2974121 0.95 CA4 (0.89) CA4ALDH1A1
Citric Acid SCHEMBL906010 0.95 CA4 (0.89) CA4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009087658-A2 COMPOSITION SUITABLE FOR PARENTERAL ADMINISTRATION SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2009-07-16 WO disclosed