Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Citric Acid SCHEMBL27913053 | 0.97 | CA4 (0.80) | CA4ALDH1A1 | |
| Citric Acid SCHEMBL4086235 | 0.97 | CA4 (0.80) | CA4ALDH1A1 | |
| Citric Acid SCHEMBL47867 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL2974121 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL906010 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL7004500 | 0.97 | CA4 (0.89) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL5311584 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL1940651 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL237100 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 | |
| Citric Acid SCHEMBL9405454 | 0.94 | CA4 (0.84) | CA4ALDH1A1CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587182-B1 | Process for producing compositions for ruminants | KYOWA HAKKO KOGYO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0600441-B1 | Laser marking and printing ink therefor | DAINIPPON INK & CHEMICALS (JP) | 1997-07-02 | — | — | EP | disclosed |
| EP-0601444-B1 | Label printing apparatus | KIRIN BREWERY (JP) | 1996-08-28 | — | — | EP | disclosed |
| US-5528280-A | Label printing apparatus for laser printing a heat-sensitive color developing ink layer of the label | KIRIN BEER KABUSHIKI KAISHA (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5413629-A | Background color inhibitor | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1995-05-09 | — | — | US | disclosed |
| EP-0601444-A1 | Label printing apparatus | KIRIN BEER KABUSHIKI KAISHA (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0600441-A1 | Laser marking and printing ink therefor | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1994-06-08 | — | — | EP | disclosed |
| EP-0587182-A2 | Process for producing compositions for ruminants | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1994-03-16 | — | — | EP | disclosed |