Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533876 | 0.84 | ALDH1A1 (0.46) | ALDH1A1ALOX15KDM4EHPGDHMGB1 | |
| SCHEMBL7820247 | 0.80 | ALDH1A1 (0.64) | ALDH1A1ALOX15KDM4EHPGDHMGB1 | |
| SCHEMBL28193157 | 0.79 | KDM4E (0.41) | ALDH1A1ALOX15KDM4EHPGDHMGB1 | |
| SCHEMBL7220374 | 0.78 | L3MBTL1 (0.44) | ALDH1A1ALOX15KDM4EHPGDHMGB1 | |
| SCHEMBL142530 | 0.77 | ALDH1A1 (0.65) | ALDH1A1ALOX15KDM4EHPGDHMGB1 | |
| SCHEMBL10572853 | 0.76 | MAPT (0.52) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4014026 | 0.76 | KDM4E (0.58) | ALDH1A1KDM4EHPGDHMGB1CA12 | |
| SCHEMBL3244289 | 0.75 | USP2 (0.51) | ALDH1A1ALOX15KDM4ESMN1; SMN2MAPT | |
| SCHEMBL7221153 | 0.75 | HPGD (0.47) | ALDH1A1ALOX15KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL526049 | 0.75 | ALDH1A1 (0.56) | ALDH1A1ALOX15KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | ALDH1A1 3748/4885ALOX15 1208/4885KDM4E 1890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.