Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.67 |
| ▸ | CA2 | P00918 | 5/20 | 0.67 |
| ▸ | CA12 | O43570 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5919563 | 0.86 | CA1 (0.76) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL26699284 | 0.84 | CA1 (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL28158752 | 0.84 | CA1 (0.69) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2295789 | 0.83 | CA12 (0.66) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7605430 | 0.83 | CA1 (0.67) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL991967 | 0.83 | CA1 (0.67) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL10135093 | 0.83 | CA1 (0.71) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL27029805 | 0.83 | CA1 (0.67) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL11862063 | 0.81 | CA1 (0.65) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL7809146 | 0.81 | ALDH1A1 (0.62) | CA1CA2CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942600-B | Preparation method of edoxaban | 内蒙古京东药业有限公司 | 2021-08-20 | — | — | CN | claimed |
| US-12606524-B2 | Synthesis of pyrrole acid derivatives | Infex Therapeutics Limited (GB) | 2026-04-21 | — | — | US | disclosed |
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | Infex Therapeutics Limited (GB) | 2026-02-10 | — | — | US | disclosed |
| EP-3810615-B1 | ARGINASE INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2026-01-28 | — | — | EP | disclosed |
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | BIOLEXIS THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4608810-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | Septerna, Inc. (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-119100967-A | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-12-10 | — | — | CN | disclosed |
| CN-114728902-B | 1-Aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | 英菲克斯治疗有限公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118307515-A | Antibacterial compounds | 英菲克斯治疗有限公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024091498-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS | SEPTERNA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
| EP-0991412-A4 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARM INC (US) | 2000-06-21 | — | — | EP | disclosed |
| EP-0991412-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | Cubist Pharmaceuticals, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5824657-A | ANTICARCINOGENIC AGENTS, SKIN DISORDERS AND PSORIASIS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-10-20 | — | — | US | disclosed |
| WO-1998041215-A1 | AMINOACYL SULFAMIDES FOR THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS | CUBIST PHARMACEUTICALS, INC. (US) | 1998-09-24 | — | — | WO | disclosed |
| US-5726195-A | Aminoacyl adenylate mimics as novel antimicrobial and antiparasitic agents | CUBIST PHARMACEUTICALS, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997005132-A1 | AMINOACYL ADENYLATE MIMICS AS NOVEL ANTIMICROBIAL AND ANTIPARASITIC AGENTS | CUBIST PHARMACEUTICALS, INC. (US) | 1997-02-13 | — | — | WO | disclosed |
| US-5273993-A | Antiarthritic agents; osteoporosis | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-12-28 | — | — | US | disclosed |
| US-5194446-A | Antiarthritic agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-16 | — | — | US | disclosed |
| US-5192785-A | Sulfamates as antiglaucoma agents | A. H. ROBINS COMPANY, INCORPORATED (US) | 1993-03-09 | — | — | US | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12544359-B2 | 1-aminosulfonyl-2-carboxypyrrole derivatives as metallo-beta-lactamase inhibitors | CBR1, CBR3, SRR | CA1 745/4885CA2 78/4885CA12 409/4885 |
| US-12606524-B2 | Synthesis of pyrrole acid derivatives | SRR, ME1, CD79B | CA1 1236/4885CA2 414/4885CA12 1554/4885 |
| US-20250388571-A1 | AMP-ACTIVATED PROTEIN KINASE MODULATOR COMPOUNDS AND USES THEREOF | PRKAB2, PRKAB1, PRKAR2B | CA1 3591/4885CA2 752/4885CA12 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.