SCHEMBL409197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL412498	0.93	CHEK1 (0.35)	KDM4EALDH1A1SMN1; SMN2CHEK1TUBB4A
	SCHEMBL413232	0.91	TUBB1 (0.40)	CHEK1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL412706	0.84	TUBB4A (0.44)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL412195	0.84	GAA (0.48)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL412810	0.84	SMPD3 (0.39)	KDM4EALDH1A1SMN1; SMN2CHEK1TUBB4A
	SCHEMBL408964	0.84	TUBB4A (0.43)	ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL413185	0.84	TUBB4A (0.54)	KDM4EALDH1A1TUBB4ATUBBTUBA3C
	SCHEMBL410977	0.83	PDGFRB (0.41)	ALDH1A1CHEK1TUBB4ATUBBTUBA3C
	SCHEMBL411699	0.83	CHEK1 (0.46)	KDM4EALDH1A1SMN1; SMN2CHEK1TUBB4A
	SCHEMBL412488	0.83	SLC10A2 (0.41)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.