SCHEMBL412498

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL409197	0.93	KDM4E (0.38)	CHEK1SMN1; SMN2NPC1RAB9ATUBB4A
	SCHEMBL413232	0.89	TUBB1 (0.40)	CHEK1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL412706	0.87	TUBB4A (0.44)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL412195	0.82	GAA (0.48)	NPC1TP53RAB9ATUBB4ATUBB
	SCHEMBL408964	0.82	TUBB4A (0.43)	TP53TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL412810	0.82	SMPD3 (0.39)	CHEK1SMN1; SMN2TUBB4ATUBBTUBA3C
	SCHEMBL413185	0.82	TUBB4A (0.54)	NPC1TP53RAB9ATUBB4ATUBB
	SCHEMBL412488	0.81	SLC10A2 (0.41)	TP53TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL411699	0.81	CHEK1 (0.46)	CHEK1SMN1; SMN2TP53TUBB4ATUBB
	SCHEMBL410977	0.81	PDGFRB (0.41)	CHEK1TP53TSHRTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.