SCHEMBL412810

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL408964	0.90	TUBB4A (0.43)	SMPD3ALDH1A1KMT2ATUBB4ATUBB
	SCHEMBL412488	0.88	SLC10A2 (0.41)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL411699	0.88	CHEK1 (0.46)	ALDH1A1MEN1KMT2ATUBB4ATUBB
	SCHEMBL410977	0.88	PDGFRB (0.41)	ALDH1A1TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL408130	0.87	ALDH1A1 (0.48)	ALDH1A1MEN1KMT2ATUBB4ATUBB
	SCHEMBL412052	0.86	KDM4E (0.45)	ALDH1A1MEN1KMT2AGAATUBB4A
	SCHEMBL408859	0.86	MAPT (0.41)	ALDH1A1MEN1KMT2ATUBB4ATUBB
	SCHEMBL413232	0.86	TUBB1 (0.40)	TUBB4ATUBBTUBA3CTUBA1BTUBA4A
	SCHEMBL413185	0.84	TUBB4A (0.54)	ALDH1A1MEN1KMT2AGAATUBB4A
	SCHEMBL409197	0.84	KDM4E (0.38)	ALDH1A1MEN1KMT2AGAATUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.