Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 2/20 | 0.31 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5607849 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL4059545 | 0.75 | MAOA (0.33) | KDM4EHTTSMN1; SMN2EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL4094393 | 0.75 | MAOA (0.33) | KDM4EHTTSMN1; SMN2EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL4092756 | 0.75 | MAOA (0.33) | KDM4EHTTSMN1; SMN2EDNRBEDNRA | |
| SCHEMBL29049893 | 0.74 | MAOA (0.35) | KDM4EHTTKDM1AMAOAKDM1B | |
| Hydrochloric Acid SCHEMBL27505811 | 0.74 | MAOA (0.32) | KDM4EHTTSMN1; SMN2EDNRBEDNRA | |
| Hydrochloric Acid SCHEMBL18112870 | 0.74 | ESR1 (0.33) | KDM4EHTTSMN1; SMN2EDNRBEDNRA | |
| SCHEMBL27479178 | 0.73 | MAOA (0.34) | EDNRBEDNRAKDM1AMAOAKDM1B | |
| Hydrochloric Acid SCHEMBL6907014 | 0.72 | KDM1A (0.32) | KDM4ESMN1; SMN2EDNRBEDNRAKDM1A | |
| SCHEMBL18114327 | 0.72 | MAOA (0.33) | EDNRBEDNRAKDM1AMAOAKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202316-B2 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-10 | — | — | US | disclosed |
| US-20050192178-A1 | Modified particle, catalyst component for addition polymerization, catalyst for addition polymerization and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-09-01 | — | — | US | disclosed |