SCHEMBL4093175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL921473	0.86	ESR1 (0.52)	HSD17B1ESRRAMAPTPKMHSP90AA1
	SCHEMBL5752711	0.83	MAPT (0.59)	HSD17B1ESRRAMAPTHPGDRAB9A
	SCHEMBL4091829	0.81	MAPT (0.58)	ESRRAMAPTHPGDRAB9APOLB
	SCHEMBL385574	0.81	PKM (0.75)	HSD17B1HPGDPKMPOLBHSP90AA1
	SCHEMBL8636430	0.80	LTA4H (0.59)	MAPTHPGDPKMPOLBHSP90AA1
	SCHEMBL921158	0.80	ESR1 (0.46)	HSD17B1MAPTPKMPOLBHSP90AA1
	SCHEMBL203697	0.78	HPGD (1.00)	ESRRAMAPTHPGDRAB9APOLB
	SCHEMBL3301210	0.78	HPGD (1.00)	ESRRAMAPTHPGDRAB9APOLB
	SCHEMBL4096708	0.78	HSD17B1 (1.00)	HSD17B1MAPTHPGDPKMPOLB
	SCHEMBL680470	0.78	MAPT (0.73)	ESRRAMAPTHPGDRAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.