SCHEMBL4093252

SCHEMBL4093252

Cc1c(C)c(C(=O)P=O)c(-c2ccccc2)c(-c2ccccc2)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.37
TSHR P16473 2/20 0.37
PDE10A Q9Y233 1/20 0.37
MAPT P10636 5/20 0.36
ALDH1A1 P00352 5/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 3/20 0.36
GAA P10253 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
RAB9A P51151 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36
FABP4 P15090 3/20 0.36
DHODH Q02127 1/20 0.36
FABP3 P05413 2/20 0.35
ERAP1 Q9NZ08 1/20 0.34
MEN1 O00255 2/20 0.33
PPARG P37231 2/20 0.33
KMT2A Q03164 2/20 0.33
NR2E3 Q9Y5X4 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19642675 0.88 SMN1; SMN2 (0.41) LMNATSHRPDE10AMAPTALDH1A1
SCHEMBL241255 0.82 SMN1; SMN2 (0.41) LMNATSHRPDE10AMAPTALDH1A1
SCHEMBL7202337 0.81 MAPT (0.41) LMNAMAPTALDH1A1SMN1; SMN2KDM4E
SCHEMBL28501630 0.79 MAPT (0.51) LMNAMAPTALDH1A1SMN1; SMN2KDM4E
SCHEMBL27476638 0.77 ALDH1A1 (0.38) LMNATSHRPDE10AMAPTALDH1A1
SCHEMBL1666977 0.77 SMN1; SMN2 (0.50) LMNATSHRMAPTALDH1A1SMN1; SMN2
SCHEMBL10832124 0.76 PDE10A (0.50) LMNATSHRPDE10AMAPTALDH1A1
SCHEMBL6294085 0.74 LMNA (0.48) LMNATSHRMAPTALDH1A1KMT2A
SCHEMBL27816594 0.74 PDE10A (0.47) LMNATSHRPDE10AMAPTALDH1A1
SCHEMBL698685 0.73 GAA (0.47) LMNATSHRMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112724724-B Fuel cell membrane electrode gas diffusion layer and preparation method and application of microporous layer thereof 永安行科技股份有限公司 2021-07-06 CN claimed
CN-112724724-A Fuel cell membrane electrode gas diffusion layer and preparation method and application of microporous layer thereof 永安行科技股份有限公司 2021-04-30 CN claimed
US-12583948-B2 Photohardenable compositions, methods, and a stabilizer QUADRATIC 3D, INC. (US) 2026-03-24 US disclosed
US-12291662-B2 Photon upconversion nanocapsules for 3D printing and other applications PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-05-06 US disclosed
WO-2025034474-A1 3D PRINTED POROUS SUPRAMOLECULAR SORBENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-02-13 WO disclosed
EP-3887480-B1 PHOTON UPCONVERSION NANOCAPSULES FOR 3D PRINTING AND OTHER APPLICATIONS HARVARD COLLEGE (US) 2024-02-14 EP disclosed
US-20240018277-A1 PHOTOHARDENABLE COMPOSITIONS, METHODS, AND A STABILIZER QUADRATIC 3D, INC. 2024-01-18 US disclosed
US-20230363984-A1 DENTAL COMPOSITION TERAUCHI ENDO INSTITUTE (JP) 2023-11-16 US disclosed
WO-2023009204-A1 COMPOSITIONS, METHODS FOR FORMING AN ARTICLE, AND PRODUCTS THEREOF QUADRATIC 3D, INC. (US) 2023-02-02 WO disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
US-20220305724-A1 TRIPLET EXCITON ACCEPTORS FOR INCREASING UPCONVERSION THRESHOLDS FOR 3D PRINTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-09-29 US disclosed
US-20180110683-A1 DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS MITSUI CHEMICALS, INC. (JP) 2018-04-26 US disclosed
EP-3278787-A1 POLYMERIZABLE MONOMER FOR DENTAL MATERIALS, COMPOSITION, ADHESIVE DENTAL MATERIAL, AND KIT Mitsui Chemicals, Inc. (JP) 2018-02-07 EP disclosed
US-8362105-B2 Dental curable composition and kit for such dental curable composition SUN MEDICAL CO., LTD. (JP) 2013-01-29 US disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SUN MEDICAL CO., LTD. (JP) 2009-05-28 US disclosed
US-20080182919-A1 Dental Restorative Composition SUN MEDICAL CO., LTD. (JP) 2008-07-31 US disclosed
EP-1938781-A1 DENTAL CURABLE COMPOSITION AND KIT FOR SUCH DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2008-07-02 EP disclosed
EP-1854447-A1 DENTAL RESTORATION MATERIAL COMPOSITION SUN MEDICAL CO., LTD. (JP) 2007-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080182919-A1 Dental Restorative Composition PARG, PARN, FHIT LMNA 682/4885TSHR 3228/4885PDE10A 2835/4885
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 LMNA 740/4885TSHR 2961/4885PDE10A 1098/4885
US-12583948-B2 Photohardenable compositions, methods, and a stabilizer NOX4, LCP1, TERB1 LMNA 2710/4885TSHR 2035/4885PDE10A 651/4885
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SETDB1, SETD1B, SETD2 LMNA 2339/4885TSHR 4302/4885PDE10A 1964/4885
US-20180110683-A1 DENTAL POLYMERIZABLE MONOMERS, COMPOSITIONS, ADHESIVE DENTAL MATERIALS AND KITS HRH3, HRH1, HRH2 LMNA 2937/4885TSHR 861/4885PDE10A 3244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.