SCHEMBL409339

SCHEMBL409339

CC(C)(C)C1CC(=O)CCN1C(=O)O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.32
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28870268 0.83
SCHEMBL2866944 0.82 RIPK1 (0.30) RIPK1
SCHEMBL17317706 0.82
SCHEMBL19995843 0.81 KDM4E (0.39)
SCHEMBL17599560 0.78 POLB (0.33) POLB
SCHEMBL7974127 0.78 CHRNA7 (0.33)
SCHEMBL7974123 0.78 CHRNA7 (0.33)
SCHEMBL192685 0.78
SCHEMBL2159514 0.76 GAA (0.30)
SCHEMBL17593010 0.76 GAA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4737441-A1 METHOD FOR PRODUCING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND FUJIFILM Corporation (JP) 2026-05-06 EP disclosed
US-20260070931-A1 METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2026-03-12 US disclosed
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS AG (CH) 2026-03-12 US disclosed
US-20250367173-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME LIGACHEM BIOSCIENCES INC (KR) 2025-12-04 US disclosed
EP-4169925-B1 PROCESS TO MAKE N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES NOVARTIS AG (CH) 2025-11-19 EP disclosed
US-12331060-B2 N-substituted tetrahydrothienopyridine derivatives and uses thereof NOVARTIS AG (CH) 2025-06-17 US disclosed
WO-2025106910-A1 DEGRADER MOLECULES TARGETING ANDROGEN RECEPTOR FLARE THERAPEUTICS INC. (US) 2025-05-22 WO disclosed
CN-116444495-B Indolone FLT3 protein degradation agent, preparation method and medical application thereof 南京中医药大学 2025-05-13 CN disclosed
WO-2025004786-A1 METHOD FOR PRODUCING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND 富士フイルム株式会社 2025-01-02 WO disclosed
US-20240352030-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. 2024-10-24 US disclosed
WO-2002016365-A1 PYRAZOLE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS FOR MODULATING OR INHIBITING ERAB OR HADH2 ACTIVITY AGOURON PHARMACEUTICALS, INC. (US) 2002-02-28 WO disclosed
EP-1173170-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Merck & Co., Inc. (US) 2002-01-23 EP disclosed
EP-1171122-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Merck & Co., Inc. (US) 2002-01-16 EP disclosed
US-6265434-B1 ANTIINFLAMMATORY AGENTS MERCK & CO., INC. 2001-07-24 US disclosed
WO-2001043740-A1 ANTIPSYCHOTIC HETEROCYCLE COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2001-06-21 WO disclosed
US-6248755-B1 ANTIINFLAMMATORY AGENTS; ANTIALLERGENS; AUTOIMMUNE DISEASES MERCK & CO., INC. 2001-06-19 US disclosed
EP-1083178-A1 Tetrahydroquinazoline-2,4-diones and therapeutic uses thereof Pfizer Products Inc. (US) 2001-03-14 EP disclosed
WO-2000059498-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed
WO-2000059502-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed
WO-2000059503-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367173-A1 ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE-1 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME ENPP1, ENPP3, SMPD1 POLB 830/4885RIPK1 4628/4885
US-12331060-B2 N-substituted tetrahydrothienopyridine derivatives and uses thereof TPMT, NNMT, NLN POLB 1516/4885RIPK1 2160/4885
US-20240352030-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF TPMT, SARS1, NLN POLB 1900/4885RIPK1 2136/4885
US-20260070931-A1 METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND TRPA1, ALK, MAFK POLB 1334/4885RIPK1 2874/4885
US-20260070920-A1 N-SUBSTITUTED TETRAHYDROTHIENOPYRIDINE DERIVATIVES AND USES THEREOF CCR3, SCN1B, NR3C1 POLB 1497/4885RIPK1 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.