Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099470 | 0.91 | NR1H4 (0.56) | NR1H4FFAR1POLBEPHX2ALDH1A1 | |
| SCHEMBL4100570 | 0.89 | S1PR1 (0.51) | NR1H4FFAR1POLBEPHX2S1PR1 | |
| SCHEMBL4100884 | 0.88 | S1PR1 (0.53) | NR1H4POLBEPHX2S1PR1 | |
| SCHEMBL4104361 | 0.83 | MEN1 (0.54) | NR1H4FFAR1POLBALDH1A1 | |
| SCHEMBL4109710 | 0.80 | FFAR1 (0.53) | NR1H4FFAR1FFAR4POLBKEAP1 | |
| SCHEMBL659263 | 0.80 | NR1H4 (0.59) | NR1H4FFAR1FFAR4KEAP1ALDH1A1 | |
| SCHEMBL8915282 | 0.79 | FFAR1 (0.60) | NR1H4FFAR1FFAR4KEAP1ALDH1A1 | |
| SCHEMBL7479986 | 0.79 | FFAR1 (0.60) | NR1H4FFAR1FFAR4POLBKEAP1 | |
| SCHEMBL11135027 | 0.79 | TSHR (0.61) | NR1H4FFAR1FFAR4POLB | |
| SCHEMBL8201608 | 0.77 | POLB (0.55) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | MALLE GERARD | 2009-08-06 | — | — | US | disclosed |
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | L'OREAL S.A. | 2009-06-04 | — | — | US | disclosed |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | L'OREAL S.A. (FR) | 2005-06-23 | — | — | US | disclosed |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | L'OREAL | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139537-A1 | HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE | KRT18, INMT, INHA | NR1H4 2905/4885FFAR1 874/4885FFAR4 1558/4885 |
| US-20090194124-A1 | Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine | KRT18, KIT, PRDM7 | NR1H4 3875/4885FFAR1 4333/4885FFAR4 3934/4885 |
| US-20050129645-A1 | Hair shaping composition comprising at least one non-hydroxide imine | KRT18, INHA, H1-5 | NR1H4 3427/4885FFAR1 4144/4885FFAR4 3848/4885 |
| US-20050136017-A1 | Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin | BHMT, KRT18, INMT | NR1H4 2022/4885FFAR1 911/4885FFAR4 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.