SCHEMBL4094237

SCHEMBL4094237

CC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Hf](Cl)Cl

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.36
HTR1A P08908 2/20 0.36
ALDH1A1 P00352 4/20 0.33
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CYP2A6 P11509 1/20 0.33
BRD4 O60885 1/20 0.33
DHFR P00374 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
KDM4E B2RXH2 3/20 0.32
HPGD P15428 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TDP2 O95551 1/20 0.32
MAPT P10636 1/20 0.32
ALOX12 P18054 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP3 P42574 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8204448 0.83 DHFR (0.34) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL8202026 0.83 HTR7 (0.34) HTR7HTR1AALDH1A1CA12CA1
Hydrochloric Acid SCHEMBL4482811 0.82 HTR1A (0.32) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL4079021 0.81 PDCD1 (0.33) HTR7HTR1ACYP2A6BRD4
Hydrochloric Acid SCHEMBL7933036 0.79 SLC22A12 (0.31) HTR7HTR1ACA12CA1CA2
SCHEMBL5860453 0.79 ALDH1A1 (0.37) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL17952999 0.79 ALDH1A1 (0.37) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL30229819 0.79 ALDH1A1 (0.37) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL8202886 0.79 ALDH1A1 (0.34) HTR7HTR1AALDH1A1CA12CA1
SCHEMBL8200938 0.78 ALDH1A1 (0.34) HTR7HTR1AALDH1A1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406339-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2021-10-26 CN disclosed
CN-107074679-B Method and apparatus for producing alpha-olefin oligomer 三菱化学株式会社 2020-11-17 CN disclosed
CN-107406345-B Process for producing alpha-olefin oligomer 三菱化学株式会社 2020-08-11 CN disclosed
CN-107428629-B α -Process for producing olefin oligomer 三菱化学株式会社 2020-07-28 CN disclosed
WO-2009104782-A1 ETHYLENE HOMOPOLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104785-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
WO-2009104783-A1 CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-08-27 WO disclosed
US-6201069-B1 POLYPROPYLENE AND ETHYLENE-PROPYLENE COPOLYMER BLENDS CHISSO CORPORATION (JP) 2001-03-13 US disclosed