Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15724407 | 0.81 | KAT2B (0.41) | BRD4L3MBTL1PARP1KAT2BSMN1; SMN2 | |
| SCHEMBL4095238 | 0.80 | KCNH2 (0.35) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL2599810 | 0.75 | ALDH1A1 (0.40) | PARP1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL12444946 | 0.74 | KAT2B (0.56) | BRD4L3MBTL1KAT2BKMT2AMEN1 | |
| SCHEMBL4094763 | 0.74 | PDE4B (0.32) | ALDH1A1 | |
| SCHEMBL2229144 | 0.72 | NTRK1 (0.36) | BRD4L3MBTL1PARP1SMN1; SMN2POLB | |
| SCHEMBL4084945 | 0.71 | DYRK1A (0.41) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14854378 | 0.71 | BRD4 (0.51) | BRD4L3MBTL1PARP1KMT2AMEN1 | |
| SCHEMBL4045955 | 0.71 | LMNA (0.65) | BRD4L3MBTL1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5338984 | 0.71 | SMN1; SMN2 (0.46) | BRD4L3MBTL1KAT2BKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |