Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL3132581 | 0.97 | ACHE (0.40) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| Methacrylic Acid SCHEMBL630757 | 0.97 | ACHE (0.40) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL525052 | 0.88 | ACHE (0.46) | ACHETDP1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL472550 | 0.88 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL10405560 | 0.88 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL3132587 | 0.88 | ACHE (0.38) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL181998 | 0.82 | THRB (0.37) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL4094910 | 0.82 | TSHR (0.43) | ACHETDP1HRH4HRH3 | |
| SCHEMBL18812881 | 0.81 | CHRNB2 (0.34) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL630756 | 0.81 | ACHE (0.34) | ACHECHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9028254-B2 | Dental prosthetics comprising curable acrylate polymer compositions and methods of their use | SCIENTIFIC PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130302513-A1 | DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE | SCIENT PHARMACEUTICALS INC (US) | 2013-11-14 | — | — | US | disclosed |
| US-20090239969-A1 | DENTAL PROSTHETICS COMPRISING CURABLE ACRYLATE POLYMER COMPOSITIONS AND METHODS OF THEIR USE | SCIENTIFIC PHARMACEUTICALS, INC (US) | 2009-09-24 | — | — | US | disclosed |
| US-20060035997-A1 | Curable acrylate polymer compositions featuring improved flexural characteristics | SCIENTIFIC PHARMACEUTICALS, INC. | 2006-02-16 | — | — | US | disclosed |