SCHEMBL409556

SCHEMBL409556

C=CC(=O)Nc1ccccc1OCOCC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.54
▸ MCL1 Q07820 1/20 0.54
▸ EGFR P00533 1/20 0.53
▸ GAA P10253 1/20 0.51
▸ KMT2A Q03164 4/20 0.50
▸ ALDH1A1 P00352 3/20 0.49
▸ MAPT P10636 1/20 0.49
▸ PKM P14618 1/20 0.49
▸ HTT P42858 1/20 0.49
▸ NLRP1 Q9C000 1/20 0.49
▸ CYP2C19 P33261 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ NPC1 O15118 3/20 0.46
▸ POLB P06746 1/20 0.45
▸ TSHR P16473 2/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ MAPK3 P27361 1/20 0.43
▸ PTK2 Q05397 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1866821 0.86 LMNA (0.50) LMNAMCL1EGFRGAAKMT2A
SCHEMBL1864641 0.83 SMN1; SMN2 (0.46) LMNAGAAKMT2AMAPTPKM
SCHEMBL1867906 0.83 CYP1A2 (0.43) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL12667254 0.82 KMT2A (0.73) LMNAMCL1EGFRGAAKMT2A
SCHEMBL1858961 0.81 GAA (0.51) LMNAMCL1EGFRGAAKMT2A
SCHEMBL1862565 0.80 FGFR4 (0.41) LMNAALDH1A1MAPTCYP2C19
SCHEMBL14031075 0.80 RAB9A (0.52) GAAKMT2AALDH1A1MAPTKDM4E
SCHEMBL1858964 0.78 HPGD (0.46) LMNAGAAKMT2AALDH1A1MAPT
SCHEMBL1379751 0.77 SMN1; SMN2 (0.67) LMNAEGFRGAAKMT2AALDH1A1
SCHEMBL10027955 0.77 KMT2A (0.80) LMNAGAAKMT2AALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120021357-A1 POSITIVE-TYPE PHOTOSENSITIVE INSULATING RESIN COMPOSITION, AND PATTERN FORMING METHOD USING SAME NEC CORPORATION (JP) 2012-01-26 — — US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 — — US disclosed
US-7939241-B2 (Meth)acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2011-05-10 — — US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 — — US disclosed
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method NEC CORPORATION (JP) 2009-03-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068587-A1 (Meth) acrylamide derivative, polymer, chemically amplified photosensitive resin composition, and patterning method MMAB, DNMT3A, MAT1A LMNA 4190/4885MCL1 2515/4885EGFR 3514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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