SCHEMBL490926

SCHEMBL490926

Brc1ccc(Nc2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.72
HSD17B10 Q99714 5/20 0.72
TDP1 Q9NUW8 4/20 0.72
ALOX12 P18054 3/20 0.72
L3MBTL1 Q9Y468 3/20 0.72
TSHR P16473 3/20 0.72
ALOX15 P16050 2/20 0.72
MAPK1 P28482 2/20 0.72
PTGS1 P23219 1/20 0.72
SLC6A2 P23975 1/20 0.72
PTGS2 P35354 1/20 0.72
HTR2B P41595 1/20 0.72
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
MAPT P10636 6/20 0.58
MAOA P21397 2/20 0.58
MAOB P27338 2/20 0.58
CYP3A4 P08684 4/20 0.56
HPGD P15428 3/20 0.56
HTT P42858 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922950 0.93 ALDH1A1 (0.64) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
Diphenylamine SCHEMBL1185801 0.92 HSD17B10 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL13148721 0.88 CYP2A6 (0.57) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL409605 0.88 CYP2A6 (0.57) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL16526973 0.88 CYP2A6 (0.57) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL3660281 0.87 ALDH1A1 (0.71) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL13663470 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL9480038 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
SCHEMBL7896372 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1
N,N'-Diphenyl-P-Phenylenediamine SCHEMBL42930 0.85 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1ALOX12L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 481 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119505419-B Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-06-03 CN claimed
CN-119505419-A Anti-aging reinforced PP (Polypropylene) daily plastic product and preparation method thereof 广东百文科技实业有限公司 2025-02-25 CN claimed
CN-116895749-B Lithium battery anode material and preparation method thereof 智泰新能源(东台)有限公司 2024-11-01 CN claimed
CN-115716787-B Alkyl fluorene small molecular compound and preparation method and application thereof 天津大学 2024-02-13 CN claimed
CN-117448062-A Aromatic amine polyurea hub bearing lubricating grease and preparation method thereof 安徽腾盛化学有限公司 2024-01-26 CN claimed
CN-116895749-A Lithium battery anode material and preparation method thereof 智泰新能源(东台)有限公司 2023-10-17 CN claimed
CN-114249295-B One-dimensional organic nanotube synthesized through covalent bond or coordination bond and method 中国科学院理化技术研究所 2023-04-18 CN claimed
CN-115716787-A Alkyl fluorene micromolecule compound and preparation method and application thereof 天津大学 2023-02-28 CN claimed
CN-114249295-A One-dimensional organic nanotube synthesized through covalent bond or coordination bond and method 中国科学院理化技术研究所 2022-03-29 CN claimed
US-12628551-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2026-05-12 US disclosed
CN-121974848-A Quinoline anti-aging agent and preparation method thereof 山东阳谷华泰化工股份有限公司 2026-05-05 CN disclosed
EP-3620448-B1 AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2026-04-08 EP disclosed
US-20260028325-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2026-01-29 US disclosed
US-12464887-B2 Light-emitting element, lighting device, light-emitting device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2025-11-04 US disclosed
WO-2001019829-A2 PYRAZOLOPYRIMIDINES AS THERAPEUTIC AGENTS BASF AKTIENGESELLSCHAFT (DE) 2001-03-22 WO disclosed
EP-0602616-B1 Process for producing 4-nitrosodiphenylamines or their salts SUMITOMO CHEMICAL CO (JP) 1997-08-27 EP disclosed
US-5648543-A FROM DIPHENYLAMIE AND NITROGEN OXIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0602616-A1 Process for producing 4-nitrosodiphenylamines or their salts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-06-22 EP disclosed
US-4485114-A Arylglyoxals useful as hypoglycemic agents AMERICAN CYANAMID COMPANY (US) 1984-11-27 US disclosed
EP-0114389-A2 Substituted arylglyoxal derivatives AMERICAN CYANAMID COMPANY (US) 1984-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028325-A1 AROMATIC AMINE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE ADRA1D, CRY1, AHR ALDH1A1 73/4885HSD17B10 3656/4885TDP1 1722/4885
US-12628551-B2 Organic light-emitting device LEF1, TBL2, RFT1 ALDH1A1 130/4885HSD17B10 1078/4885TDP1 3605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.