Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28360369 | 0.80 | PTGS1 (0.38) | ALDH1A1HNF4APTGS1MEN1KMT2A | |
| SCHEMBL6974190 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 | |
| SCHEMBL8529625 | 0.79 | PTGS2 (0.38) | ALDH1A1HNF4APTGS1MEN1KMT2A | |
| SCHEMBL28755647 | 0.78 | DHODH (0.47) | ALDH1A1HNF4APTGS1MEN1KMT2A | |
| SCHEMBL4849742 | 0.76 | ALDH1A1 (0.51) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 | |
| SCHEMBL14690430 | 0.76 | HNF4A (0.59) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 | |
| SCHEMBL17309702 | 0.76 | HNF4A (0.50) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 | |
| SCHEMBL8530215 | 0.76 | MEN1 (0.39) | ALDH1A1HNF4APTGS1MEN1KMT2A | |
| SCHEMBL17309706 | 0.73 | HNF4A (0.50) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 | |
| SCHEMBL27489890 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HNF4AMEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815919-B2 | Oxadiazole derivatives | MERCK SERONO SA (CH) | 2014-08-26 | — | — | US | disclosed |
| US-20120022109-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO SA (CH) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022109-A1 | OXADIAZOLE DERIVATIVES | OXA1L, HLA-DRB1, SSB | ALDH1A1 510/4885HNF4A 2407/4885PTGS1 839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.