SCHEMBL4096876

SCHEMBL4096876

CC(C)N(C)c1ccccc1C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
ALOX15 P16050 1/20 0.48
MAPT P10636 4/20 0.47
GAA P10253 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
KDM4E B2RXH2 5/20 0.46
HPGD P15428 3/20 0.46
GLA P06280 1/20 0.46
HDAC8 Q9BY41 1/20 0.45
LMNA P02545 2/20 0.42
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HMGB1 P09429 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27713499 0.85 ALDH1A1 (0.47) ALDH1A1MAPTGAASMN1; SMN2TP53
SCHEMBL14150723 0.84 ALDH1A1 (0.52) ALDH1A1ALOX15MAPTGAASMN1; SMN2
SCHEMBL29129834 0.83 IRAK4 (0.47) ALDH1A1MAPTGAASMN1; SMN2TP53
SCHEMBL16674515 0.81 TP53 (0.44) ALDH1A1MAPTGAASMN1; SMN2TP53
SCHEMBL18158039 0.79 ALDH1A1 (0.56) ALDH1A1ALOX15MAPTGAASMN1; SMN2
Phthalic Acid SCHEMBL8925302 0.79 ALDH1A1 (0.64) ALDH1A1ALOX15MAPTSMN1; SMN2KDM4E
SCHEMBL15240 0.79 ALDH1A1 (0.72) ALDH1A1ALOX15MAPTGAASMN1; SMN2
SCHEMBL4333889 0.79 ALDH1A1 (0.46) ALDH1A1ALOX15MAPTGAASMN1; SMN2
SCHEMBL27823469 0.79 ALDH1A1 (0.60) ALDH1A1ALOX15MAPTGAASMN1; SMN2
SCHEMBL4245598 0.78 ALDH1A1 (0.45) ALDH1A1ALOX15MAPTGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2491915-B1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO LTD (JP) 2019-07-03 EP disclosed
US-8362105-B2 Dental curable composition and kit for such dental curable composition SUN MEDICAL CO., LTD. (JP) 2013-01-29 US disclosed
EP-2491915-A1 EASILY REMOVABLE CURABLE COMPOSITION FOR DENTAL USE SUN MEDICAL CO., LTD. (JP) 2012-08-29 EP disclosed
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2012-08-23 US disclosed
US-20090258966-A1 Dental Composition NIHON UNIVERSITY (JP) 2009-10-15 US disclosed
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SUN MEDICAL CO., LTD. (JP) 2009-05-28 US disclosed
CN-101242802-A Dental curable composition and kit for such dental curable composition SUN MEDICAL CO LTD (JP) 2008-08-13 CN disclosed
EP-1938781-A1 DENTAL CURABLE COMPOSITION AND KIT FOR SUCH DENTAL CURABLE COMPOSITION SUN MEDICAL CO., LTD. (JP) 2008-07-02 EP disclosed
US-7294183-B2 Activating agents for use with reactive colorants in inkjet printing of textiles HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-11-13 US disclosed
US-7294183-B2 Activating agents for use with reactive colorants in inkjet printing of textiles HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-11-13 US disclosed
EP-0923924-B1 Dental adhesive kit SUN MEDICAL CO LTD (JP) 2005-03-09 EP disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
US-6071983-A FOR TREATING TOOTH SURFACE BY FACILE HANDLING; FOR RESTORING A TOOTH-SURFACE WITH COATING MATERIAL OR RESTORING DENTAL RESTORATIVE RESINS SUN MEDICAL CO., LTD. (JP) 2000-06-06 US disclosed
EP-0684034-B1 Primer solution composition for dental bonding SUN MEDICAL CO LTD (JP) 2000-03-08 EP disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed
US-5834532-A BLEND OF POLYMERIZABLE MONOMER HAVING ACIDIC GROUPS AND AN INITIATOR SUN MEDICAL CO., LTD. (JP) 1998-11-10 US disclosed
US-5670559-A TREATMENT OF TEETH WITH COMPOUNDS OF IRON, COPPER AND COBALT SUN MEDICAL CO., LTD. (JP) 1997-09-23 US disclosed
US-5587406-A APPLYING CURABLE PRIMER COMPOSITION COMPRISING POLYMERIZABLE MONOMER HAVING ACID GROUP AND POLYMERIZABLE MONOMER HAVING HYDROXYL GROUP AND POLYMERIZATION INITIATOR TO TOOTH SUN MEDICAL CO., LTD. (JP) 1996-12-24 US disclosed
US-5530038-A CONTAINING UNSATURATED MONOMER WITH ACIDIC GROUP, UNSATURATED MONOMER WITH HYDROXYL GROUP, POLYMERIZATION INITIATOR, AMINE COMPOUND, ZIRCONIUM OXIDE AND ORGANIC COMPOSITE FILLERS SUN MEDICAL CO., LTD. (JP) 1996-06-25 US disclosed
EP-0684034-A1 Primer solution composition for dental bonding SUN MEDICAL CO., LTD. (JP) 1995-11-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258966-A1 Dental Composition DCPS, MMAB, CAD ALDH1A1 1892/4885ALOX15 3322/4885MAPT 592/4885
US-20120213832-A1 REMOVABLE DENTAL CURABLE COMPOSITION SMARCA5, SMARCA1, SMARCA2 ALDH1A1 1369/4885ALOX15 1640/4885MAPT 1563/4885
US-20090137697-A1 Dental Curable Composition and Kit for Such Dental Curable Composition SETDB1, SETD1B, SETD2 ALDH1A1 1260/4885ALOX15 1895/4885MAPT 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.