Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14150723 | 0.82 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPTHDAC8AKR1C3 | |
| SCHEMBL4096876 | 0.79 | ALDH1A1 (0.48) | ALDH1A1ALOX15MAPTHDAC8LMNA | |
| SCHEMBL8779567 | 0.79 | KMT2A (0.49) | ALDH1A1SMN1; SMN2POLBHPGDCA12 | |
| SCHEMBL829847 | 0.78 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2TP53POLB | |
| SCHEMBL4245598 | 0.76 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTHDAC8LMNA | |
| SCHEMBL11517103 | 0.75 | SIGMAR1 (0.47) | ALDH1A1MAPTLMNASMN1; SMN2TP53 | |
| SCHEMBL8614764 | 0.75 | ALDH1A1 (0.44) | ALDH1A1LMNASMN1; SMN2TP53KDM4E | |
| SCHEMBL1046327 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPTHDAC8LMNA | |
| SCHEMBL27823469 | 0.74 | ALDH1A1 (0.60) | ALDH1A1ALOX15MAPTHDAC8LMNA | |
| SCHEMBL2543696 | 0.74 | ALDH1A1 (0.63) | ALDH1A1LMNASMN1; SMN2TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |