Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596110 | 0.86 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL6269788 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTSMN1; SMN2KMT2A | |
| SCHEMBL7566566 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL10599602 | 0.82 | MEN1 (0.45) | ALDH1A1SMN1; SMN2LMNAKMT2AGAA | |
| SCHEMBL14150723 | 0.81 | ALDH1A1 (0.52) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL4096876 | 0.78 | ALDH1A1 (0.48) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL4333889 | 0.76 | ALDH1A1 (0.46) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL4249310 | 0.76 | ALDH1A1 (0.50) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL29980356 | 0.75 | ALOX5 (0.47) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL28549723 | 0.75 | ALOX5 (0.47) | ALDH1A1ALOX15MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131527-A1 | NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME | CLIC1, ASIC1, CLIC4 | ALDH1A1 1179/4885ALOX15 397/4885MAPT 4324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.