Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146560 | 0.83 | TSHR (0.63) | ALDH1A1TSHRCES2CES1ALOX15 | |
| SCHEMBL161331 | 0.83 | KDM4E (0.53) | ALDH1A1TSHRCES2CES1POLB | |
| SCHEMBL1189439 | 0.81 | TSHR (0.45) | ALDH1A1TSHRCES2CES1POLB | |
| SCHEMBL2473273 | 0.80 | MMP2 (0.47) | ALDH1A1TSHRALOX15RECQLHPGD | |
| SCHEMBL29016414 | 0.78 | HDAC8 (0.47) | ALDH1A1TSHRCES2CES1POLB | |
| SCHEMBL2533018 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TSHRCES2CES1POLB | |
| SCHEMBL28234218 | 0.78 | TSHR (0.42) | ALDH1A1TSHRCES2CES1POLB | |
| SCHEMBL93365 | 0.77 | TSHR (0.68) | ALDH1A1TSHRCES2CES1ALOX15 | |
| SCHEMBL3917269 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRALOX15HPGDKMT2A | |
| SCHEMBL28144990 | 0.77 | MAPT (0.43) | ALDH1A1TSHRCES2CES1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232531-A | A kind of preparation method of the card than replacing Buddhist nun | 安庆奇创药业有限公司 | 2019-01-18 | — | — | CN | claimed |
| CN-109232531-A | A kind of preparation method of the card than replacing Buddhist nun | 安庆奇创药业有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-104496967-A | Substituent N heterozygous aromatic base amide compound and application thereof | UNIV NANKAI | 2015-04-08 | — | — | CN | disclosed |
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-08-20 | — | — | US | disclosed |
| WO-2008157500-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209536-A1 | AMINOQUINAZOLINE CANNABINOID RECEPTOR MODULATORS FOR TREATMENT OF DISEASE | CNR2, CNR1, GPR18 | ALDH1A1 4857/4885TSHR 3396/4885CES2 3628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.