Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 3/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4100038 | 0.90 | PTGES (0.60) | PTGESPTPN11MCL1PPARDCYP3A4 | |
| SCHEMBL3582187 | 0.87 | PTGES (0.67) | PTGESMCL1KEAP1NFE2L2CYP1A2 | |
| SCHEMBL4101074 | 0.83 | PTGES (0.54) | PTGESMCL1KEAP1NFE2L2CYP1A2 | |
| SCHEMBL4089205 | 0.83 | PTGES (0.56) | PTGESMCL1KEAP1NFE2L2CYP1A2 | |
| SCHEMBL4095194 | 0.81 | PTPN11 (0.41) | PTGESPTPN11MCL1CYP3A4CYP3A5 | |
| SCHEMBL4090259 | 0.80 | PTGES (0.61) | PTGESPTPN11MCL1KEAP1NFE2L2 | |
| SCHEMBL4104398 | 0.78 | PPARG (0.41) | PTGESPTPN11PPARDPPARA | |
| SCHEMBL4096749 | 0.77 | PTGES (0.47) | PTGESPTPN11PTGDRSCN9APPARA | |
| SCHEMBL3578404 | 0.77 | PTGES (0.53) | PTGESSCN9AMCHR1DGAT1 | |
| SCHEMBL3571641 | 0.77 | PTGES (0.53) | PTGESCYP1A2PPARDSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048285-A1 | Pyrrolopyridines Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048285-A1 | Pyrrolopyridines Useful in the Treatment of Inflammation | PYCR1, ARG2, ARG1 | PTGES 47/4885PTPN11 1154/4885MCL1 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.