Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4089205 | 0.93 | PTGES (0.56) | PTGESPTGDRSCN9ACYP3A4CYP3A5 | |
| SCHEMBL3582187 | 0.87 | PTGES (0.67) | PTGESMCL1KEAP1NFE2L2PPARG | |
| SCHEMBL4096749 | 0.86 | PTGES (0.47) | PTGESPTGDRSCN9AHTTPPARG | |
| SCHEMBL4097026 | 0.83 | PTGES (0.52) | PTGESPTGDRSCN9ACYP3A4CYP3A5 | |
| SCHEMBL4923306 | 0.83 | PTGES (0.52) | PTGESSCN9A | |
| SCHEMBL4090259 | 0.83 | PTGES (0.61) | PTGESCYP3A4CYP3A5MCL1KEAP1 | |
| SCHEMBL4228522 | 0.81 | PTGES (0.59) | PTGESSCN9A | |
| SCHEMBL4268491 | 0.78 | PTGES (0.60) | PTGESMCL1KEAP1NFE2L2TEAD1 | |
| SCHEMBL3570895 | 0.77 | PTGES (0.83) | PTGESMCL1PPARGALDH1A1TEAD1 | |
| SCHEMBL4097221 | 0.77 | PTGES (0.55) | PTGESSCN9AMCL1PPARGTEAD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048285-A1 | Pyrrolopyridines Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-02-19 | — | — | US | disclosed |
| EP-1841766-A1 | PYRROLOPYRIDINES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006077401-A1 | PYRROLOPYRIDINES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048285-A1 | Pyrrolopyridines Useful in the Treatment of Inflammation | PYCR1, ARG2, ARG1 | PTGES 47/4885PTGDR 157/4885SCN9A 3473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.