Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31568708 | 0.73 | OXTR (0.33) | GAAMAPTOXTRKDM4EPKM | |
| SCHEMBL18243851 | 0.73 | OXTR (0.33) | GAAMAPTOXTRKDM4EPKM | |
| SCHEMBL2857845 | 0.71 | HTR2C (0.34) | PDK2 | |
| SCHEMBL6310235 | 0.71 | PDK2 (0.35) | PDK2 | |
| SCHEMBL29842453 | 0.70 | GAA (0.36) | GAAMAPTOXTRKDM4EPKM | |
| SCHEMBL2287265 | 0.70 | GAA (0.36) | GAAMAPTOXTRKDM4EPKM | |
| SCHEMBL6049920 | 0.70 | HTR2C (0.36) | PDK2 | |
| SCHEMBL29390519 | 0.68 | MAPT (0.36) | PDK2GAAMAPTOXTRKDM4E | |
| SCHEMBL22584880 | 0.67 | GAA (0.33) | GAAMAPTOXTRKDM4EPKM | |
| SCHEMBL18573347 | 0.67 | GAA (0.33) | GAAMAPTOXTRKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225162-B1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PROD & CHEM (US) | 2005-03-16 | — | — | EP | claimed |
| US-20030100806-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | LAL GAURI SANKAR (US) | 2003-05-29 | — | — | US | claimed |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | VERSUM MATERIALS US, LLC | 2002-12-26 | — | — | US | claimed |
| US-6455744-B1 | MIXING SOLUTION OF A TETRAFLUORO DERIVATIVE OF AN AROMATIC COMPOUND IN AN ORGANIC SOLVENT WITH REDUCING AGENT IN AQUEOUS AMMONIA, UNDER AN INERT GAS, TO FORM AN AROMATIC COMPOUND CONTAINING TWO VICINAL FLUORINE ATOMS | AIR PRODUCTS AND CHEMICALS, INC. | 2002-09-24 | — | — | US | claimed |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | AIR PRODUCTS AND CHEMICALS, INC. | 2002-07-25 | — | — | US | claimed |
| EP-1225162-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-07-24 | — | — | EP | claimed |
| CN-101903364-A | Thiazoline urea and amide derivatives and methods of use thereof | ABBOTT LAB | 2010-12-01 | — | — | CN | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | PROSIDION LIMITED (GB) | 2009-09-03 | — | — | US | disclosed |
| CN-101155817-A | Dihydroimidazothiazole derivatives | PROSIDION LTD (GB) | 2008-04-02 | — | — | CN | disclosed |
| EP-1851232-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | Prosidion Limited (GB) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006085118-A2 | DIHYDROIMIDAZOTHIAZOLE DERIVATIVES | PROSIDION LIMITED (GB) | 2006-08-17 | — | — | WO | disclosed |
| US-20030149315-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | VERSUM MATERIALS US, LLC | 2003-08-07 | — | — | US | disclosed |
| US-20030100806-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | LAL GAURI SANKAR (US) | 2003-05-29 | — | — | US | disclosed |
| US-6515191-B2 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. | 2003-02-04 | — | — | US | disclosed |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | VERSUM MATERIALS US, LLC | 2002-12-26 | — | — | US | disclosed |
| US-6455744-B1 | MIXING SOLUTION OF A TETRAFLUORO DERIVATIVE OF AN AROMATIC COMPOUND IN AN ORGANIC SOLVENT WITH REDUCING AGENT IN AQUEOUS AMMONIA, UNDER AN INERT GAS, TO FORM AN AROMATIC COMPOUND CONTAINING TWO VICINAL FLUORINE ATOMS | AIR PRODUCTS AND CHEMICALS, INC. | 2002-09-24 | — | — | US | disclosed |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | AIR PRODUCTS AND CHEMICALS, INC. | 2002-07-25 | — | — | US | disclosed |
| EP-1225162-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149315-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | HAAO, PAH, PFAS | PDK2 2071/4885GAA 1741/4885MAPT 3771/4885 |
| US-20030100806-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | PAH, AHR, HAAO | PDK2 1554/4885GAA 2023/4885MAPT 2625/4885 |
| US-20090221645-A1 | Dihydroimidazothiazole Derivatives | TPH1, HTR3B, HTR1A | PDK2 1256/4885GAA 1098/4885MAPT 891/4885 |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | PAH, AHR, HAAO | PDK2 1554/4885GAA 2023/4885MAPT 2625/4885 |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | PAH, AHR, HAAO | PDK2 1554/4885GAA 2023/4885MAPT 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.