SCHEMBL4098151

SCHEMBL4098151

COc1ccc(C(=O)c2ccc(OCc3cc(-c4ccccc4)on3)cc2)c(OC(C)(C)C(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.50
PPARG P37231 5/20 0.45
SLC6A9 P48067 1/20 0.44
POLB P06746 1/20 0.43
KDM4E B2RXH2 2/20 0.43
PPARD Q03181 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 1/20 0.42
PTPN1 P18031 2/20 0.42
NPC1 O15118 2/20 0.42
ALOX5 P09917 1/20 0.41
MAPT P10636 3/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
PGR P06401 1/20 0.40
CYP2D6 P10635 1/20 0.40
HPGD P15428 1/20 0.40
SLC6A2 P23975 1/20 0.40
PDE4A P27815 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4102102 0.84 GSTP1 (0.54) PPARANPC1MAPTMAPK1TDP1
SCHEMBL4100378 0.84 L3MBTL1 (0.55) PPARGPOLBPTPN1NPC1MAPT
SCHEMBL4102084 0.83 SMPD1 (0.51) PPARAPPARGPOLBPPARDNPC1
SCHEMBL4096147 0.83 PPARG (0.49) PPARAPPARGPOLBKDM4EPPARD
SCHEMBL4107394 0.82 PPARG (0.63) PPARAPPARGPOLBKDM4EPPARD
SCHEMBL4109168 0.80 PTGER4 (0.47) PPARAPPARGPOLBKDM4EPPARD
SCHEMBL4108188 0.79 PPARG (0.51) PPARAPPARGPOLBKDM4EPPARD
SCHEMBL4103807 0.79 PPARA (0.58) PPARAPPARGPOLBPPARDMAPT
SCHEMBL4097643 0.78 PPARG (0.57) PPARAPPARGPOLBKDM4EPPARD
SCHEMBL4098899 0.78 PPARG (0.54) PPARAPPARGPOLBKDM4EPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054435-A1 Phenoxyalkanoic Acid Compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-02-26 US disclosed
EP-1911738-A1 PHENOXYALKANOIC ACID COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054435-A1 Phenoxyalkanoic Acid Compound PNLIP, GPR119, LIPC PPARA 8/4885PPARG 23/4885SLC6A9 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.