Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | C1R | P00736 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551154 | 0.85 | ABCG2 (0.42) | IDO1PBRM1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL11624680 | 0.75 | IDO1 (0.53) | IDO1LMNAHSD17B10ALDH1A1MAPK1 | |
| SCHEMBL206363 | 0.75 | IDO1 (0.53) | IDO1PBRM1LMNAHSD17B10ALDH1A1 | |
| SCHEMBL2277157 | 0.75 | IDO1 (0.53) | IDO1ALDH1A1DCUN1D1RAB9ANPC1 | |
| SCHEMBL1176838 | 0.75 | METAP2 (0.30) | — | |
| SCHEMBL30497931 | 0.75 | IDO1 (0.53) | IDO1ALDH1A1DCUN1D1RAB9ANPC1 | |
| SCHEMBL6693198 | 0.75 | DCUN1D1 (0.41) | IDO1HSD17B10ALDH1A1MAPK1DCUN1D1 | |
| SCHEMBL1857660 | 0.75 | IDO1 (0.53) | IDO1HSD17B10ALDH1A1DCUN1D1MAPT | |
| SCHEMBL3252001 | 0.75 | IDO1 (0.55) | IDO1HSD17B10ALDH1A1DCUN1D1NR1H2 | |
| SCHEMBL6349171 | 0.75 | POLB (0.31) | LMNAALDH1A1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458543-A | Dry powder inhalers | 3M INNOVATIVE PROPERTIES CO | 2012-05-16 | — | — | CN | claimed |
| CN-113166140-B | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-113166140-A | CDK8/19 inhibitors | 拜奥卡德联合股份公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-112566901-A | Phenyl-substituted pyrazoles as modulators of ROR γ t | 詹森药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-112079780-A | Bipyrazole compound and preparation method thereof | 怀化学院 | 2020-12-15 | — | — | CN | disclosed |
| CN-111747988-A | Organic electroluminescent material and device | 环球展览公司 | 2020-10-09 | — | — | CN | disclosed |
| CN-109651443-A | Electroluminescent organic material and device | 环球展览公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-104093715-A | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | ACTELION PHARMACEUTICALS LTD | 2014-10-08 | — | — | CN | disclosed |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
| US-20060035866-A1 | Phosphonate compounds having immuno-modulatory activity | GILEAD SCIENCES, INC. | 2006-02-16 | — | — | US | disclosed |
| EP-1620110-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004100960-A2 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
| WO-2004096236-A2 | IMMUNOMODULATOR PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |
| US-20040170547-A1 | Process for removing metals from liquids | BRISTOL-MYERS SQUIBB COMPANY | 2004-09-02 | — | — | US | disclosed |
| WO-2004052286-A2 | TYROSINE KINASE INHIBITORS | MERCK & CO., INC. (US) | 2004-06-24 | — | — | WO | disclosed |
| WO-2004052488-A2 | PROCESS FOR REMOVING METALS FROM LIQUIDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| CN-1049658-C | Pyrazolo[4,3-c]pyridines, a process for their preparation and their use as serotonin reuptake inhibitors | HOECHST MARION ROUSSEL INC (US) | 2000-02-23 | — | — | CN | disclosed |
| CN-1099033-A | Pyrazolo [4,3-c] pyridine, their preparation method and as the purposes of serotonin reuptake inhibitors | HOECHST ROUSSEL PHARMA (US) | 1995-02-22 | — | — | CN | disclosed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035866-A1 | Phosphonate compounds having immuno-modulatory activity | PHOSPHO1, NFATC1, IFNG | IDO1 59/4885PBRM1 1919/4885LMNA 4759/4885 |
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | IDO1 2388/4885PBRM1 3642/4885LMNA 2591/4885 |
| US-20040170547-A1 | Process for removing metals from liquids | AP2M1, AP2A1, AP2A2 | IDO1 2909/4885PBRM1 510/4885LMNA 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.